Evidence map›Paper›PMID 40838041›Full record

ArticleDementia & neuropsychologia2025

Cerebral inflammatory amyloid angiopathy: response to treatment.

João Roberto Ribeiro Pimenta, Júlian Letícia Freitas, Maria Sheila Guimarães Rocha, Sonia Maria Dozzi Brucki

Abstract readCase Reports
In one paragraph

Article in Dementia & neuropsychologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

João Roberto Ribeiro PimentaHospital Santa Marcelina, Departamento de Neurologia, São Paulo SP, Brazil.ORCID https://orcid.org/0000-0003-2609-2890
Júlian Letícia FreitasHospital Santa Marcelina, Departamento de Neurologia, São Paulo SP, Brazil.ORCID https://orcid.org/0000-0002-7119-3423
Maria Sheila Guimarães RochaHospital Santa Marcelina, Departamento de Neurologia, São Paulo SP, Brazil.ORCID https://orcid.org/0000-0003-4312-3994
Sonia Maria Dozzi BruckiHospital Santa Marcelina, Departamento de Neurologia, São Paulo SP, Brazil.ORCID https://orcid.org/0000-0002-8303-6732

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral Amyloid Angiopathy (CAA) is a small vessel disease associated with β-amyloid (Aβ) deposition in cortical and leptomeningeal vessels. Traditionally diagnosed through invasive methods, it can now be identified via advanced imaging modalities, enhancing non-invasive diagnostic accuracy. A subset of patients exhibits an inflammatory presentation, termed Inflammatory Cerebral Amyloid Angiopathy (CAA-RI), characterized by cognitive decline, behavioral changes, and neurological deficits. This study highlighted two cases of CAA-RI with subacute onset, detailed clinical progression, and distinct MRI findings consistent with revised diagnostic criteria, enabling early suspicion. Both cases showed significant improvement with immunosuppressive therapy, reinforcing the potentially reversible nature of CAA-RI and the importance of early recognition. This article underscores the relevance of advanced imaging in the differential diagnosis of CAA and the potential for improved patient outcomes with timely treatment.

Indexed as

Amyloid Beta-PeptidesCerebral Amyloid AngiopathyImmunosuppression TherapyMagnetic Resonance Imaging

Identifiers

PMID40838041
PMCPMC12364481

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.