Evidence map›Paper›PMID 40838021›Full record

ArticlePNAS nexus2025

In utero exposure to extreme heat increases neonatal mortality.

Tenghui Wang, Jiafu An, Bin Chen, Chris John Webster, Peng Gong, Chen Lin

Abstract read
In one paragraph

Article in PNAS nexus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tenghui WangDepartment of Finance, Faculty of Business, Lingnan University, Hong Kong SAR 999077, China.ORCID https://orcid.org/0000-0003-3836-3678
Jiafu AnDepartment of Real Estate and Construction, Faculty of Architecture, The University of Hong Kong, Hong Kong SAR 999077, China.ORCID https://orcid.org/0000-0002-3025-3119
Bin ChenFuture Urbanity & Sustainable Environment (FUSE) Lab, Division of Landscape Architecture, Faculty of Architecture, The University of Hong Kong, Hong Kong SAR 999077, China.ORCID https://orcid.org/0000-0003-3496-2876
Chris John WebsterUrban Environments and Human Health Lab, Faculty of Architecture, Hong Kong SAR 999077, China.ORCID https://orcid.org/0000-0002-2171-7495
Peng GongDepartment of Geography, The University of Hong Kong, Hong Kong SAR 999077, China.ORCID https://orcid.org/0000-0003-1513-3765
Chen LinFaculty of Business and Economics, The University of Hong Kong, Hong Kong SAR 999077, China.ORCID https://orcid.org/0000-0003-4205-8633

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sub-Saharan Africa (SSA) has had the highest neonatal mortality rate in the world for the past few decades. In 2021, 27 infants died within the first month of life for every thousand live births in SSA, accounting for 54% of infant deaths (0-12 months) on the continent. Meanwhile, extreme heat events are occurring with increasingly higher frequency in this region due to climate change, worsening the living and health conditions for already vulnerable populations. Despite the prominence of high neonatal mortality rates and the frequent occurrence of extreme weather events in SSA, it remains unclear whether in-utero exposure to extreme heat is a significant contributing factor. Our research investigates this question using granular data on extreme heat and birth records from 33 African countries drawn from the Demographic and Health Surveys. It collects nationally representative, repeated cross-sectional surveys that assess reproductive and health behaviors across the developing countries every 5 years. Employing a measure of heat that simultaneously accounts for the impact of humidity, we show that a cumulative increase of 150 °C in extreme heat exposure during the 9-month pregnancy period is associated with two additional neonatal deaths per thousand live births. Mothers with lower economic status or limited education experience a more pronounced negative impact from exposure to extreme heat, likely due to reduced prenatal care. Our results are relevant to policymakers aiming to curb the negative impacts of climate change by better targeting the victims of extreme heat and developing effective adaptation strategies.

Identifiers

PMID40838021
PMCPMC12362353

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.