Evidence map›Paper›PMID 40837915›Full record

ArticleCureus2025

Triple Threat: Co-occurrence of Serous Borderline Ovarian Tumor, Endometrial Adenocarcinoma, and Low-Grade Appendiceal Mucinous Neoplasms With Pseudomyxoma Peritonei in a Single Patient.

Ana Djordjevic, Aleksandar Rakic, Smiljana Donic, Nenad Pavlovic, Lazar Nejkovic

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ana DjordjevicDepartment of Obstetrics and Gynecology, Obstetrics and Gynecology Clinic Narodni Front, Belgrade, SRB.
Aleksandar RakicDepartment of Obstetrics and Gynecology, Obstetrics and Gynecology Clinic Narodni Front, Belgrade, SRB.
Smiljana DonicDepartment of Obstetrics and Gynecology, Obstetrics and Gynecology Clinic Narodni Front, Belgrade, SRB.
Nenad PavlovicDepartment of Pathology, Obstetrics and Gynecology Clinic Narodni Front, Belgrade, SRB.
Lazar NejkovicDepartment of Obstetrics and Gynecology, Obstetrics and Gynecology Clinic Narodni Front, Belgrade, SRB.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Borderline ovarian tumors (BOTs) are epithelial ovarian neoplasms characterized by cellular proliferation and nuclear atypia without stromal invasion. On the other hand, low-grade appendiceal mucinous neoplasms (LAMNs) have features such as mucin production, a distinct invasion pattern, and low-grade cytological characteristics. Pseudomyxoma peritonei (PMP), an uncommon disorder characterized by mucinous peritoneal dispersion, can be exacerbated by both BOTs and LAMNs. We present a case of a 63-year-old patient who was diagnosed with a serous BOT, LAMN with PMP, and synchronous endometrioid endometrial cancer. After episodes of postmenopausal bleeding, an explorative curettage confirmed the diagnosis of endometrioid endometrial cancer. Since the preoperative ultrasound showed a tumorous mass in the right adnexa and retrouterine space, the patient had an explorative laparotomy. A right ovarian tumor, hepatic and omental deposits, and an appendiceal lesion were among the intraoperative findings. A hysterectomy was performed along with peritoneal biopsy, cytological analysis of peritoneal lavage, bilateral salpingo-oophorectomy, omentectomy, lymphadenectomy, and appendectomy. Histopathological examination verified the presence of BOT, LAMN with PMP, and endometrial cancer. This case highlights the diagnostic difficulties of synchronous gastrointestinal and gynecological neoplasms and emphasizes the significance of a multidisciplinary surgical approach and thorough preoperative examination. According to our knowledge, this is the first case of synchronous endometrial cancer, serous BOT, and LAMN with PMP.

Indexed as

endometrial cancer (ec)low-grade appendiceal mucinous neoplasmpseudomyxoma peritoneiserous borderline ovarian tumorsynchronous neoplasms

Identifiers

PMID40837915
PMCPMC12362045

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.