Evidence map›Paper›PMID 40837913›Full record

ArticleCureus2025

Biochemical Profiles in Hypertension: Ferritin, Antioxidant Enzymes, and Mineral Levels in Blood Serum.

Mohamed Salem, James Robenson

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mohamed SalemBiomedical Sciences, Penn State Health Milton S. Hershey Medical Center, Hershey, USA.
James RobensonNeurosurgery, AdventHealth Orlando, Orlando, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate the level of ferritin and some biochemical indices in patients with hypertension. The total number of samples taken was 90, including 60 from hypertensive patients (Group 1: 30 female patients and 30 male patients) aged between 25 and 55 years, and another 30 specimens from healthy individuals (Group 2: 15 female patients and 15 male patients). Samples were obtained from an open-access repository that aggregates information from multiple sources. Specific collection locations were not disclosed to ensure confidentiality and generalizability of the findings. This study assessed concentrations of ferritin, cholesterol, catalase, malondialdehyde (MDA), peroxidase, nitrite, sodium, and potassium in the blood serum. The results showed that Group 1 has higher levels of serum ferritin than the control group, which are significantly different among male patients, but no significant difference between male and female subjects in the control group. Findings revealed that Group 1 had lower cholesterol levels compared to those without high blood pressure. Catalase levels did not differ significantly between groups, although they were found to be higher in male patients of Group 1. Malondialdehyde level was significantly higher in Group 1 as compared to the control group, while peroxidase activity showed no significant difference between groups. Sodium concentration was significantly greater for Group 1, whereas potassium concentration was the highest in the control group. This demonstrates how these biomarkers could help understand hypertension more clearly and suggests potential research areas requiring closer clinical attention.

Indexed as

antioxidant enzymesferritin levelshypertensionoxidative stressserum biomarkers

Identifiers

PMID40837913
PMCPMC12361825

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.