ArticleCureus2025
Rapid Progression of Oral Leukoplakia to Oral Squamous Cell Carcinoma in an HIV-Positive Patient: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
HIV patients are at an increased risk of developing head and neck cancers, particularly due to the immunocompromised state caused by the virus. This report aims to illustrate a case of a HIV-positive patient whose oral leukoplakia rapidly progressed into oral squamous cell carcinoma. The patient was initially referred to our Department of Oral Medicine and Pathology, School of Dentistry, Aristotle University of Thessaloniki, Greece, on May 17, 2024, due to the presence of an intraoral lesion. The examination revealed a white plaque lesion on his left buccal mucosa, which was subjected to biopsy. The histopathological examination showed a moderately dysplastic leukoplakia. The patient was advised to follow bimonthly checkups, and on July 9, 2024, he was reexamined. The second examination revealed an alteration of the clinical appearance of an exophytic mass, and the patient underwent a second biopsy. This time, the lesion was proven to be an early invasive oral squamous cell carcinoma, surrounded by moderately dysplastic leukoplakia. This case signifies the necessity of regular follow-ups in patients manifesting oral potentially malignant disorders. HIV-positive individuals necessitate proactive monitoring, due to the immunosuppression, in order to detect potentially malignant disorders and malignancies at an early, treatable stage.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.