Evidence map›Paper›PMID 40837829›Full record

ArticleJournal of oral biology and craniofacial research

Oral thin film containing rice husk liquid smoke effects on the expression of key cytokines and growth factors in a periodontitis model.

Gustiadi Saputra, Ira Arundina, Theresia Indah Budhy, Dieni Mansur, Meircurius Dwi Condro Surboyo, Cheng Hwee Ming, Sheryn Marcha Ramaniasari, Azzahra Salsabila Adira Moelyanto

Abstract read
In one paragraph

Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gustiadi SaputraPoliteknik Kesehatan Kesuma Bangsa, Bandar Lampung, Indonesia.
Ira ArundinaDepartment of Oral Biology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, 60132, Indonesia.
Theresia Indah BudhyDepartment of Oral Pathology and Maxillofacial, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, 60132, Indonesia.
Dieni MansurResearch Center for Chemistry, National Research and Innovation Agency, B.J. Habibie Science and Technopark, Serpong, South Tangerang 15314, Banten, Indonesia.
Meircurius Dwi Condro SurboyoDepartment of Oral Medicine, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, 60132, Indonesia.
Cheng Hwee MingDepartment Physiology. Faculty of Medicine. University of Malaya, Kuala Lumpur, 50603, Malaysia.
Sheryn Marcha RamaniasariMagister of Dental Health Science, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, 60132, Indonesia.
Azzahra Salsabila Adira MoelyantoMagister of Dental Health Science, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, 60132, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Objective: This study aimed to formulate and characterize an oral thin film (OTF) containing rice husk liquid smoke and evaluate its antibacterial activity and biological effects in a periodontitis model. Methods: OTFs were prepared using hydroxypropyl methylcellulose, gelatin, sorbitol, and rice husk liquid smoke via solvent casting. The OTF were characterized for weight, thickness, swelling, disintegration, dissolution, and antibacterial activity against Results: The OTFs showed favorable physical properties, including low weight, appropriate thickness, and faster disintegration and dissolution times (p < 0.05). Both OTF and blank films inhibited Conclusion: The OTF containing rice husk liquid smoke exhibited strong antibacterial and immunomodulatory effects, suggesting its potential as a novel therapeutic strategy for periodontitis.

Indexed as

InflammationLiquid smokeOral thin filmPeriodontitisPorphyromonas gingivalis

Identifiers

PMID40837829
PMCPMC12362671

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.