ArticleWorld journal of psychiatry2025
Global burden of mental disorders in 204 countries and territories results from the Global Burden of Disease Study 2021.
Article in World journal of psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Lifestyle Factors Associated with Perceived Stress Among Adolescents: The Indirect Role of Mediterranean Diet Adherence in the Screen Time-Stress Association.Healthcare (Basel, Switzerland) · 2026Article
- Folate and global health: part 5. syntheses on neuropsychiatric disorders.Journal of global health · 2026Review
- Racial and gender disparities in reasons for seeking mental healthcare in Canada.Discover mental health · 2026Article
- Physical Activity as a Mediator of the Relationship Between Mediterranean Diet Adherence and Anxiety Symptoms in Chilean Adolescents: A Cross-Sectional Study.Children (Basel, Switzerland) · 2026Article
- Chronotype, Genetic Risk, Lifestyle, and Risk of Depression and Anxiety: A Prospective Cohort Study.MedComm · 2026Article
- Therapeutic potential of exerkines in neurodegenerative and mental disorders: a narrative review.Frontiers in physiology · 2026Review
- Cross-Sectional and Longitudinal Associations Between Dietary Intake and Depressive Symptoms in Young South African Adults: The African-PREDICT Study.Depression and anxiety · 2026Observational
- Examining Smartphone-assessed Executive Function Metrics and Intrinsic Resting-State Functional Connectivity in Depression.Research square · 2025Article
- Editorial: Nutrition and mood disorders.Frontiers in nutrition · 2025Article
- The role of the occupational physician in the early detection of occupational diseases.Revista brasileira de medicina do trabalho : publicacao oficial da Associacao Nacional de Medicina do Trabalho-ANAMTReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMental disorders have become a major contributor to the Global Burden of Disease (GBD), a situation that has worsened with the onset of the coronavirus disease 2019 (COVID-19) pandemic. Updated data on their impact and a clear understanding of long-term trends are essential for global and national health authorities to implement effective prevention and intervention strategies for mental well-being.
aimTo generate insights that will enhance global awareness of the burden of mental disorders and support the development of targeted, region-specific prevention and intervention strategies tailored to current global and local health challenges.
methodsWe extracted data on incidence, disability-adjusted life years (DALYs), age-standardized incidence rate (ASIR), and age-standardized DALY rate (ASDR) for 12 categories of mental disorders from 1990 to 2021 across 204 countries and territories grouped into 21 regions. Trends in ASIR and ASDR were also analyzed during the COVID-19 period (2019-2021).
resultsFrom 1990 to 2021, global ASIR rose by 15.23% (12.97% to 17.60%), while ASDR increased by 73.52% (70.24% to 76.71%). All 21 GBD regions saw a rise in cases and DALYs. In 2021, Central sub-Saharan Africa had the highest ASIR (8706.11), and East Asia reported the lowest (3340.99). Australasia recorded the highest ASDR (2787.87). On the national level, Greenland, Greece, United States, and Australia had the greatest ASDR values. During the pandemic years, ASIR and ASDR rose across all five socio-demographic index levels and GBD regions, with the exception of East Asia, where rates remained stable. Females experienced a higher ASDR than males in 2021. Major depressive disorder (557.87) and anxiety disorders (524.33) were the most burdensome among the 12 types, with depressive disorders ranking first in 13 out of the 21 regions.
conclusionThe GBD study 2021 results highlight a continued and worsening global burden of mental disorders, further intensified by the COVID-19 crisis. This underscores the urgent need to reinforce mental health care systems. Special attention should be directed toward high-middle socio-demographic index areas and female populations. Expanding access to mental health services, enhancing public awareness, and delivering targeted interventions are essential to lessen the growing impact of mental disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.