Evidence map›Paper›PMID 40837655›Full record

ArticleAfrican health sciences2025

Clinical efficacy comparison of CO2 laser treatment and LEEP surgery for cervical intraepithelial neoplasia with high-risk HPV infection.

Shanshan Huang, Hongling Guo, Tingting Yu, Guojian Gu, Xiaofa Wu, Xiang Li, Yan Cheng

Abstract readComparative Study
In one paragraph

Article in African health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shanshan HuangDepartment of Gynecology, Taicang Affiliated Hospital of Soochow University, Taicang First People's Hospital, Taicang, China.
Hongling GuoDepartment of Gynecology, Taicang Affiliated Hospital of Soochow University, Taicang First People's Hospital, Taicang, China.
Tingting YuDepartment of Gynecology, Taicang Affiliated Hospital of Soochow University, Taicang First People's Hospital, Taicang, China.
Guojian GuDepartment of Pathology, Taicang Affiliated Hospital of Soochow University, Taicang First People's Hospital, Taicang, China.
Xiaofa WuDepartment of Gynecology, Taicang Affiliated Hospital of Soochow University, Taicang First People's Hospital, Taicang, China.
Xiang LiDepartment of General Practice, Taicang Affiliated Hospital of Soochow University, Taicang First People's Hospital, Taicang, China.
Yan ChengDepartment of Gynecology, Taicang Affiliated Hospital of Soochow University, Taicang First People's Hospital, Taicang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To investigate the clinical efficacy of CO2 laser and loop electrosurgical excision procedure (LEEP) in the treatment of cervical intraepithelial neoplasia (CIN) with high-risk human papillomavirus (HPV) infection. Methods: A total of 150 CIN patients with high-risk HPV infection admitted to our hospital from December 2020 to June 2022 were divided into CO2 laser treatment group (CO2 group) with 63 cases and LEEP treatment group (LEEP group) with 87 cases based on treatment principles and patient preferences. The postoperative recovery time, CIN treatment effect, high-risk HPV clearance rate, treatment safety, and recurrence rate were compared between the two groups. Results: The vaginal discharge time, vaginal bleeding time, and wound healing time in the CO2 group were significantly lower than those in the LEEP group (P < 0.05). The incidence of adverse events in the CO2 group was 14.29%, which was significantly lower than that in the LEEP group (28.74%, P < 0.05). Conclusion: CO2 laser and LEEP surgery for the treatment of CIN combined with high-risk HPV infection both have good clinical efficacy, and CO2 laser can effectively shorten the postoperative recovery time with good safety.

Indexed as

ElectrosurgeryLasers, GasLaser TherapyPapillomavirus InfectionsUterine Cervical DysplasiaUterine Cervical NeoplasmsAdultFemaleHumansMiddle AgedRetrospective StudiesTreatment Outcomecervical intraepithelial neoplasiaclinical efficacyCO2 laserhigh-risk human papillomavirusloop electrosurgical excision proceduresafety

Identifiers

PMID40837655
PMCPMC12361942

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.