Evidence map›Paper›PMID 40837624›Full record

ArticleDigital discovery2025

Optimization of robotic liquid handling as a capacitated vehicle routing problem.

Guangqi Wu, Runzhong Wang, Connor W Coley

Abstract read
In one paragraph

Article in Digital discovery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Guangqi WuDepartment of Chemical Engineering, Massachusetts Institute of Technology 77 Massachusetts Avenue Cambridge MA 02139 USA ccoley@mit.edu.
Runzhong WangDepartment of Chemical Engineering, Massachusetts Institute of Technology 77 Massachusetts Avenue Cambridge MA 02139 USA ccoley@mit.edu.ORCID https://orcid.org/0000-0002-9566-738X
Connor W ColeyDepartment of Chemical Engineering, Massachusetts Institute of Technology 77 Massachusetts Avenue Cambridge MA 02139 USA ccoley@mit.edu.ORCID https://orcid.org/0000-0002-8271-8723

Funding

Accelerated discovery of synthetic polymers for ribonucleoprotein delivery through the integration of active learning, machine learning, and polymer scienceR21GM141616 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI COLEY, CONNOR WILSON · 2021 to 2022
$427k
NIGMS NIH HHS R21 GM141616
6 · The paper itself

Abstract

We present an optimization strategy to reduce the execution time of liquid handling operations in the context of an automated chemical laboratory. By formulating the task as a capacitated vehicle routing problem (CVRP), we leverage heuristic solvers traditionally used in logistics and transportation planning to optimize task execution times. As exemplified using an 8-channel pipette with individually controllable tips, our approach demonstrates robust optimization performance across different labware formats (

Identifiers

PMID40837624
PMCPMC12360158

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.