Evidence map›Paper›PMID 40837596›Full record

ArticleJournal of clinical imaging science2025

A multireader, multicase study comparing ultra-high-resolution and conventional-resolution computed tomography for lung nodule characterization.

Andrew M Hernandez, Anthony F Chen, Fatma Sen, Ana S Mitchell, Sarah E McKenney, Lorenzo Nardo, Craig K Abbey, Mohammad H Madani

Abstract read
In one paragraph

Article in Journal of clinical imaging science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andrew M HernandezDepartment of Radiology, University of California Davis, Sacramento, California, United States.ORCID https://orcid.org/0000-0002-1806-7073
Anthony F ChenDepartment of Radiology, University of California Davis, Sacramento, California, United States.ORCID https://orcid.org/0000-0002-4591-2447
Fatma SenDepartment of Radiology, University of California Davis, Sacramento, California, United States.
Ana S MitchellDepartment of Radiology, University of California Davis, Sacramento, California, United States.
Sarah E McKenneyDepartment of Radiology, University of California Davis, Sacramento, California, United States.
Lorenzo NardoDepartment of Radiology, University of California Davis, Sacramento, California, United States.
Craig K AbbeyDepartment of Psychological and Brain Sciences, University of California, Santa Barbara, California, United States.
Mohammad H MadaniDepartment of Radiology, University of California Davis, Sacramento, California, United States.

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Gina M Dayton · 2002 to 2026
$84.9M
NCI NIH HHS P30 CA093373
6 · The paper itself

Abstract

Objectives: The objective of the study was to evaluate the efficacy of ultra-high-resolution computed tomography (UHRCT) in comparison to conventional resolution computed tomography (CT) for the characterization of lung nodules. Material and Methods: 104 non-contrast chest UHRCT scans (mean age of 66 years, 57 females) with pulmonary nodules were retrospectively collected (February-November 2022), and corresponding normal-resolution (NR) reconstructions were synthesized using a validated algorithm. Five blinded radiologists scored the following for each localized nodule in the ultra-high-resolution (UHR) and NR datasets: Margin clarity (5-point Likert scale), image quality "IQ" (3-point), density confidence (0-100%), and size (long/short axes). Image noise (voxel standard deviation) was calculated within the trachea. Differences between UHR and NR were tested using the Wilcoxon signed-rank test. Intrareader agreement was quantified with intraclass correlation coefficient (ICC), and ordinal association between margin clarity and IQ was quantified with Kendall's Results: Margin clarity, IQ, and density confidence were significantly higher for UHR ( Conclusion: UHRCT offers significant improvements in the visualization of lung nodules compared to conventional resolution CT, albeit with an increase in image noise.

Indexed as

Chest computed tomographyLung noduleUltra-high-resolution computed tomography

Identifiers

PMID40837596
PMCPMC12361665

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.