Evidence map›Paper›PMID 40837576›Full record

ArticleFrontiers in medicine2025

Associations between childhood trauma, depression, anxiety disorders and early arthritis presence.

Ana Konjikusic, Sarah Ohrndorf, Tanja Braun, Vivien Kluckow, Vera Höhne-Zimmer, Gabriela Schmittat, Christine Heim, Ralf Uebelhack, Kirsten Minden, Jacqueline Detert and 2 more

Abstract read
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Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ana KonjikusicDepartment of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Charitéplatz, Germany.
Sarah OhrndorfDepartment of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Charitéplatz, Germany.
Tanja BraunDepartment of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Charitéplatz, Germany.
Vivien KluckowDepartment of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Charitéplatz, Germany.
Vera Höhne-ZimmerDepartment of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Charitéplatz, Germany.
Gabriela SchmittatDepartment of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Charitéplatz, Germany.
Christine HeimCharité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt Universität zu Berlin, Institute of Medical Psychology, Berlin, Charitéplatz, Germany.
Ralf UebelhackDepartment of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Charitéplatz, Germany.
Kirsten MindenDeutsches Rheuma-Forschungszentrum Berlin, Epidemiology Unit, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Charitéplatz, Germany.
Jacqueline DetertRheumatologisch-immunologische Praxis Templin, Templin, Germany.
Gerd-Rüdiger BurmesterDepartment of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Charitéplatz, Germany.
Desiree SchaumburgDepartment of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Charitéplatz, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To compare the prevalence of childhood trauma, depression, and anxiety disorders between patients with early arthritis (EA) and a control group (CG). We further aimed to explore the influence of these variables on EA diagnosis. Methods and materials: This monocentric study included 60 prospectively recruited EA patients with at least one inflammatory joint with a symptom duration of 1-12 months. The CG consisted of 60 individuals with no clinical signs of arthritis. The participants underwent a semi-structured interview screening for psychiatric disorders and completed standardized questionnaires, including the Hospital Anxiety and Depression Scale (HADS-A, HADS-D), the Childhood Trauma Questionnaire (CTQ), and the Posttraumatic Diagnostic Scale (PDS). For statistical analysis, we used SPPS© χ Results: Compared to the CG, patients with EA had significantly higher rates of depression in the interview (41.7% vs. 16.7%; Conclusion: The high rates of depression and PTSD in EA emphasize a potential link between psychiatric disorders and arthritis. The presence of EA might be associated with present and lifetime depressive symptoms, childhood sexual abuse and emotional neglect.

Indexed as

anxietychildhood traumadepressionearly arthritis (EA)PTSD - posttraumatic stress disorder

Identifiers

PMID40837576
PMCPMC12361254

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