Evidence map›Paper›PMID 40837410›Full record

ReviewGenes & diseases2025

ADAMTS2: More than a procollagen N-proteinase.

Ruben Vanlerberghe, Alain Colige, Anne-Marie Malfait, Delfien Syx, Fransiska Malfait

Abstract readReview
In one paragraph

Review in Genes & diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. AnBiomedicines · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ruben VanlerbergheCenter for Medical Genetics, Ghent University Hospital, Department of Biomolecular Medicine, Ghent University, Ghent 9000, Belgium.
Alain ColigeLaboratory of Connective Tissues Biology, Tour de Pathologie, GIGA-Cancer, University of Liège, Liège 4000, Belgium.
Anne-Marie MalfaitDivision of Rheumatology, Department of Internal Medicine, Rush University Medical College, and Chicago Center on Musculoskeletal Pain, Chicago, IL 60612, United States.
Delfien SyxCenter for Medical Genetics, Ghent University Hospital, Department of Biomolecular Medicine, Ghent University, Ghent 9000, Belgium.
Fransiska MalfaitCenter for Medical Genetics, Ghent University Hospital, Department of Biomolecular Medicine, Ghent University, Ghent 9000, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAMTS2) is a member of the ADAMTS zinc metalloproteinase family, best known for its role as a procollagen I N-proteinase in the maturation of fibrillar collagens. Biallelic defects in the

Indexed as

ADAMTS2CollagenDermatosparaxisEhlers-Danlos syndromeProcollagen N-Proteinase

Identifiers

PMID40837410
PMCPMC12362006

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.