Evidence map›Paper›PMID 40837322›Full record

ArticleSurgical neurology international2025

Intracranial fungal mass imitating a high-grade glial lesion - is antifungal alone sufficient?

Warda Ahmed, Syed Ather Enam, Hafiza Fatima Aziz

Abstract readCase Reports
In one paragraph

Article in Surgical neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Warda AhmedDepartment of Surgery, Medical College, Aga Khan University, Sindh, Pakistan.
Syed Ather EnamDepartment of Neurosurgery, Section of Neurosurgery, Aga Khan University, Sindh, Pakistan.
Hafiza Fatima AzizDepartment of Neurosurgery, Dr. Ziauddin Hospital, Karachi, Sindh, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Intracranial fungal mass is rare among immunocompetent individuals with variable presentation and management algorithms making it challenging to achieve optimal outcomes. Case Description: Herein, we report the presentation of a 34-year-old immunocompetent Pashtun female with acute-onset rapidly progressing generalized weakness, altered cognition, and motor and speech deficits. Although the radiological findings resembled a glioblastoma, the strong clinical suspicion of a fungal infection and her improvement on voriconazole treatment led to the decision to avoid surgical resection, thereby minimizing the risk of potential dissemination. Conclusion: Our case emphasizes that any deviation from the typical presentation of high-grade tumors must be reviewed with the need for surgical resection being evaluated on a case-to-case basis while prioritizing patient outcomes.

Indexed as

GlioblastomaImmunocompetentIntracranial fungal massSurgeryVoriconazole

Identifiers

PMID40837322
PMCPMC12361654

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.