ArticleSurgical neurology international2025
Polymorphous low-grade neuroepithelial tumor of the young.
Article in Surgical neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a newly recognized entity first described in 2017. This article reports the clinical, radiological, histological, and molecular characteristics of PLNTY diagnosed in a young female. Case Description: A 20-year-old female, not known to have any medical illness, presented to the emergency department with speech arrest that progressed to generalized tonic-clonic seizures. Brain magnetic resonance imaging showed a T2 hyperintense nonenhancing cortical-based heterogeneous mass in the left medial temporal lobe and adjacent inferior temporal gyrus measuring 2.7 × 2 × 2.5 cm with no susceptibility signal or diffusion restriction. Electroencephalogram (EEG) showed left temporal epileptiform discharges. She underwent left frontotemporal craniotomy and tumor resection. The light microscopic examination of the tumor revealed a low-grade infiltrative neoplasm. There was a classical appearance of round cells with perinuclear halo, immunopositive for olig-2, glial fibrillary acidic protein ( Conclusion: This article reports an additional case of PLNTY, a newly defined central nervous system tumor entity, describing its clinical, radiological, histological, and molecular features.
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