Evidence map›Paper›PMID 40837150›Full record

ArticleCurrent developments in nutrition2025

Micronutrients Associated With Anemia in School-age Children and Adolescents 2005-2018: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) Project.

Rochelle Werner, Hanqi Luo, Lei Liu, Yuqing Wang, Jiaxi Geng, Yi-An Ko, Parminder S Suchdev, Yaw Addo, Zulfiqar Ahmed Bhutta, Victor Temple and 7 more

Abstract read
In one paragraph

Article in Current developments in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Rochelle WernerHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States.
Hanqi LuoHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States.
Lei LiuHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States.
Yuqing WangHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States.
Jiaxi GengDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States.
Yi-An KoDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States.
Parminder S SuchdevHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States.
Yaw AddoDivision of Nutrition, Physical Activity, and Obesity, Centers for Disease Control and Prevention, Atlanta, Georgia, United States.
Zulfiqar Ahmed BhuttaInstitute for Global Health & Development, Aga Khan University, Karachi, Pakistan.
Victor TempleDivision of Basic Medical Sciences, School of Medicine and Health Sciences, University of Papua New Guinea, Port Moresby, Papua New Guinea.
Frank WieringaFrench National Research Institute for Sustainable Development, Montpellier, France.
Fabian RohnerGroundWork, Fläsch, Switzerland.
Maria J Ramirez-LuzuriagaPhoenix Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, United States.
Reina Engle-StoneDepartment of Nutrition, Institute for Global Nutrition, UC Davis, Davis, California, United States.
Anne WilliamsHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States.
Melissa F YoungHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States.
BRINDA Workgroup

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: School-age children and adolescents may be at risk of anemia through demands on micronutrients required for growth and maturation. Objectives: This multicountry analysis examined the burden of anemia in children aged 5-19 y by sex and age category and associations with micronutrient deficiencies, inflammation, and BMI. Methods: Children aged 5-19 y from surveys in the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) Project were included with hemoglobin, ≥1 micronutrient (iron, vitamin A, folate, vitamin B Results: This analysis included 54,534 children from 17 surveys in 16 countries (16 surveys for 15-19 y; 9 surveys for 10-14 y; 8 surveys for 5-9 y). Median overall anemia prevalence was 16% (range: 5% in Ecuador, United Kingdom, and United States to 59% in Côte d'Ivoire) with the highest burden in 15-19-y-old females (24%). In most surveys, anemia prevalence did not differ by sex for children aged 5-14 y, and median anemia prevalence was lower in children aged 10-14 y (7%) than in those aged 5-9 y (9%) or 15-19 y (22%). In most surveys, higher anemia prevalence was associated ( Conclusions: Iron deficiency and vitamin A deficiency are consistently associated with anemia in school-age children and adolescents, whereas inflammation and other micronutrients had context-dependent associations. This research underscores the importance of examining multiple micronutrients associated with anemia in the context of factors such as country, age, and sex.

Indexed as

adolescentsanemiaBiomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA)body mass index (BMI)globaliron deficiency (ID)micronutrientsnutritionschool-age childrenyouth

Identifiers

PMID40837150
PMCPMC12362516

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.