Evidence map›Paper›PMID 40837129›Full record

ArticleJOR spine2025

Quantitative Sensory Testing in an Observational Cohort of Adults With Chronic Low Back Pain.

Michael J Schneider, Carol M Greco, Amanda M Acevedo, Kevin M Bell, Jessa Darwin, Anthony Delitto, Nathan E Dodds, John M Jakicic, Gina P McKernan, Charity G Patterson and 6 more

Abstract read
In one paragraph

Article in JOR spine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Michael J SchneiderDoctor of Chiropractic Program, University of Pittsburgh School of Health and Rehabilitation Sciences Pittsburgh Pennsylvania USA.
Carol M GrecoDepartment of Psychiatry University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA.ORCID https://orcid.org/0000-0002-3078-2918
Amanda M AcevedoBehavioral Research Program, National Cancer Institute Rockville Maryland USA.
Kevin M BellDepartment of Bioengineering University of Pittsburgh Swanson School of Engineering Pittsburgh Pennsylvania USA.ORCID https://orcid.org/0000-0003-2099-413X
Jessa DarwinDepartment of Physical Medicine and Rehabilitation University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA.ORCID https://orcid.org/0000-0003-3360-2043
Anthony DelittoDepartment of Physical Therapy University of Pittsburgh School of Health and Rehabilitation Sciences Pittsburgh Pennsylvania USA.
Nathan E DoddsDepartment of Psychiatry University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA.ORCID https://orcid.org/0000-0001-5465-7081
John M JakicicDepartment of Internal Medicine University of Kansas Medical Center Kansas City Kansas USA.ORCID https://orcid.org/0000-0001-6800-9368
Gina P McKernanDepartment of Physical Medicine and Rehabilitation University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA.
Charity G PattersonDepartment of Physical Therapy University of Pittsburgh School of Health and Rehabilitation Sciences Pittsburgh Pennsylvania USA.ORCID https://orcid.org/0000-0002-0060-0124
Paul A PilkonisDepartment of Psychiatry University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA.ORCID https://orcid.org/0000-0003-1075-0617
Sara R PivaClinical and Translational Science Institute, University of Pittsburgh Pittsburgh Pennsylvania USA.
Gwendolyn A SowaClinical and Translational Science Institute, University of Pittsburgh Pittsburgh Pennsylvania USA.
Nam V VoFerguson Laboratory for Orthopaedic and Spine Research, Bethel Musculoskeletal Research Center, Department of Orthopaedic Surgery University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA.
Lan YuDepartment of Medicine University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA.
Ajay D WasanDepartment of Anesthesiology and Perioperative Medicine University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA.

Funding

Influence of inflammation-related genetic variants on PT treatment response in a population affected by CLBPU19AR076725 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SOWA, GWENDOLYN A, VO, NAM V · 2019 to 2023
$21.7M
NIAMS NIH HHS U19 AR076725
6 · The paper itself

Abstract

Background: Quantitative Sensory Testing (QST), also known as psychophysical testing, includes standardized methods for assessing humans' perceptions of different types of sensory stimuli and their associated pain thresholds. QST results can be used to estimate altered or atypical sensory processing and thus can be useful for determining pain mechanisms such as nociplastic or central nervous system-mediated pain. The University of Pittsburgh Mechanistic Research Center, entitled, "Low Back Pain: Biological, Biomechanical, Behavioral Phenotypes (LB Methods: Four QST procedures were administered to participants of the LB Results: The final cohort of QST participants was 999 adults. The mean/SD of lumbar and trapezius PPTs was 4.6 (2.4) and 4.4 (1.9) kg/cm Conclusions: QST data were collected from a large cohort of individuals with cLBP who participated in the LB

Indexed as

chronic low back painconditioned pain modulationpressure pain thresholdquantitative sensory testingtemporal summation

Identifiers

PMID40837129
PMCPMC12363403

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.