ArticleACS catalysis2024
Rh(III)-Catalyzed Alkene
Article in ACS catalysis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Iron-catalysed radical difunctionalization of alkenes.Nature synthesis · 2025Article
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Authors and funding
3 authors.
Funding
Abstract
Alkene difunctionalization methods are an attractive way to rapidly build molecular complexity using readily available starting materials. One common approach is transition metal-catalyzed nucleometalation, which converts the C-C double bond to a C-Nu bond and a C-M bond. Commonly, a tethered nucleophile is used in order to form pharmaceutically relevant heterocyclic cores in this manner. The resulting alkylmetal species can then be further functionalized in a number of ways. While methods exist to aminate the C-M bond, direct installation of valuable amides is rare. Additionally, nucleometalation methods are often limited to the use of a single type of nucleophile. Herein we disclose a general method for the Rh(III)-catalyzed nucleoamidation of alkenes, forming a variety of heterocyclic cores.
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Registered trials
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