ArticleResearch and practice in thrombosis and haemostasis2025
The impact of statins on pulmonary embolism severity-a retrospective data analysis.
Article in Research and practice in thrombosis and haemostasis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Clinical Outcomes Associated with Statin Use in Pulmonary Embolism: A Systematic Review of Observational Studies.Journal of clinical medicine · 2025Review
- The role of statins in mitigating venous thromboembolism incidence and severity.Research and practice in thrombosis and haemostasis · 2025Article
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Authors and funding
12 authors.
Funding
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Abstract
Background: Recent studies have demonstrated decreased rates of venous thrombotic events, including pulmonary embolism (PE), in patients taking statins. It, however, remains elusive whether statins could also impact PE severity. Objectives: To investigate a potential association between statin use and the severity of PE in a retrospective cohort. Methods: We performed a retrospective data analysis of patients with PE confirmed by computed tomography pulmonary angiography between January 1, 2010, and December 31, 2019, at the University Hospital Graz, Austria. PE severity was assessed based on the 2019 European Society of Cardiology guidelines. Results: Of 1590 patients analyzed, 235 (14.7%) were statin users. Statin users were significantly older than nonusers (median, 74 years [IQR, 66-80] vs 67 years [IQR, 52-78]; Conclusion: Statin use was not associated with PE severity. The smaller proportion of low-risk PE in statin users is likely attributable to their older age, higher BMI, and comorbidities.
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