Evidence map›Paper›PMID 40837025›Full record

ReviewResearch and practice in thrombosis and haemostasis2025

Radiotherapy-the not-so-insignificant contributor to cancer-associated venous thrombosis.

Gerard Gurumurthy, Jacob Miller, Marc Carrier, Alok Khorana, Jecko Thachil

Abstract readReview
In one paragraph

Review in Research and practice in thrombosis and haemostasis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Antithrombotic therapy at the end-of-life-continue or stop?Research and practice in thrombosis and haemostasis · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gerard GurumurthyThe University of Manchester, Manchester, UK.
Jacob MillerDepartment of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Marc CarrierDepartment of Medicine, University of Ottawa, The Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Alok KhoranaDepartment of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Jecko ThachilMAHSC Professor, The University of Manchester, Manchester, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Venous thromboembolism is a well-established complication in patients with cancer and a leading cause of morbidity and mortality in these subjects. However, the role of radiotherapy in cancer-associated venous thromboembolism (CAT) remains less clearly defined. The incidence of CAT in this population varies widely, with several large-scale studies suggesting an association. Although management of CAT in this population follows standard guidelines, less is known about the appropriateness of thromboprophylaxis in patients with different types of cancer. Patients with cancer undergoing radiotherapy may also be at increased risk of bleeding, which may be further worsened by anticoagulation. A multidisciplinary approach integrating hematology and oncology expertise is essential in this setting. Further research is needed to establish standardized protocols and predictive models to identify those at risk of thrombosis and bleeding while on anticoagulation.

Indexed as

cancercancer-associated venous thrombosisradiation therapyradiotherapyvenous thromboembolism

Identifiers

PMID40837025
PMCPMC12362088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.