Evidence map›Paper›PMID 40836986›Full record

ArticleFrontiers in drug delivery2024

Release of delta-9-tetrahydrocannabinol from polyvinyl alcohol hydrogels and its safe interaction with human skin fibroblasts.

Shujun Cui, Ze Zhang, Denis Rodrigue, François Béland, Mahmoud Rouabhia

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in drug delivery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shujun CuiGroupe de Recherche en Écologie Buccale, Faculté de Médecine Dentaire Université Laval, Québec, QC, Canada.
Ze ZhangAxe Médecine Régénératrice Centre de Recherche du CHU de Québec-Université Laval, Département de Chirurgie Faculté de Médecine, Université Laval, Québec, QC, Canada.
Denis RodrigueChemical Engineering Department, Laval University, Québec, QC, Canada.
François BélandSiliCycle® Inc 2500, Parc-Technologique Blvd, Québec, QC, Canada.
Mahmoud RouabhiaGroupe de Recherche en Écologie Buccale, Faculté de Médecine Dentaire Université Laval, Québec, QC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to design a THC-rich hydrogel to deliver cannabis derivatives topically. We developed hydrogels using polyvinyl alcohol (PVA) mixed with propylene glycol (PG), vegetable glycerin (VG), or both to facilitate the dissolution of delta-9-tetrahydrocannabinol (THC). The hydrogels showed a brown color, confirming the presence of the cannabinoid. They exhibit a porous structure and better mechanical properties than PVA alone. Indeed, the hydrogel containing PG, VG, or both showed elastic deformation behaviors with lower water content. FTIR analysis demonstrated the presence of THC with two specific peaks at 1,575 and 1,619 cm

Indexed as

cannabiscell adhesionfibroblastshydrogelskinTHC

Identifiers

PMID40836986
PMCPMC12363267

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.