Evidence map›Paper›PMID 40836964›Full record

ArticleBiochemistry and biophysics reports2025

Identification and validation of a hypoxia- and immune-related prognostic signature for pancreatic cancer.

Ganghua Yang, Jiawei Yu, Xuqi Li, Fandi Meng, Yong Wan, Zhengyang Lu, Zheng Wang, Qinhong Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry and biophysics reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ganghua YangDepartment of Geriatric Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Jiawei YuDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Xuqi LiDepartment of General Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Fandi MengDepartment of Geriatric Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Yong WanDepartment of Geriatric Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Zhengyang LuDepartment of Geriatric Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Zheng WangDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Qinhong XuDepartment of Geriatric Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer is a lethal disease with a poor prognosis. Immunity and hypoxia are critical characteristics of the tumor microenvironment and are closely associated with cancer prognosis. The present study aimed to identify a novel hypoxia- and immune-related gene signature for the prediction of prognosis in patients with pancreatic cancer. The status of hypoxia or immunity was determined via the NMF method by using data from the TCGA database. A total of 27 hypoxia- or immune-related DEGs were identified. A 6-gene hypoxia- and immune-related prognostic signature (

Indexed as

HypoxiaImmuneNomogramPancreatic cancerPrognosis

Identifiers

PMID40836964
PMCPMC12361614

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