SynthesisBone & joint open2025
Outcomes reported in trials of children and adolescent knee injuries : a systematic review.
Synthesis in Bone & joint open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
26 authors.
Funding
Abstract
Aims: To systematically review published evidence of outcomes reported in trials of knee injuries in children and adolescents. Methods: We searched the following databases from inception to 29 July 2024: OVID MEDLINE, Embase, Cochrane CENTRAL, Clinicaltrials.gov, and the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP). In total, 13,146 studies were identified; after removing duplicates, 9,796 studies were yielded for screening following PRISMA guidelines. Data extraction was performed by two researchers, and 15 trials were included in the final analysis. Outcomes reported by trials were mapped to the domains within the WHO International Classification of Function framework (ICF), comprising four main categories: Body functions (b), Activities and participation (d), Environmental factors (e), and Body structure (s). Results: A total of 83 outcomes were identified from 15 trials, representing 35 WHO domains. The most common domain reported mapped to the ICF framework was structure of the lower limb (s750; 93.3%), followed by sensation of pain (b280; 86.7%), mobility of joint function (b710; 86.7%), and function of the joints and bones (b729; 86.7%). Patient satisfaction was reported in two trials (13.3%) trials. Primary outcomes were not reported in seven trials (46.6%). Pedi-International Knee Documentation Committee (IKDC) was the most common patient-reported outcome measure in seven trials (46.6%). Conclusion: Outcome measure tools reported in children and adolescent knee injuries are highly variable and inconsistent. Currently, there are no core outcome sets (COS) for these injuries, highlighting an urgent need to improve standardization and consistency in trial reporting. A key recommendation for the COS development is accounting for pathology-specific subcategories, given the difference in emphasis on WHO ICF domains across various knee injuries. In the future, these approaches will ensure the COS has comprehensive yet unique priorities for each condition.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.