Evidence map›Paper›PMID 40836584›Full record

ArticleClinical and translational medicine2025

CDK7 inhibition promotes glioblastoma cell death through convergent transcriptional and metabolic stress pathways.

Thomas Freitag, Jana Vanessa Scheffler, Philipp Kaps, Anne Hieltscher, Björn Schneider, Daniel Dubinski, Florian Gessler, Thomas M Freiman, Felix Wittig, Sascha Troschke-Meurer and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Thomas FreitagDepartment of Medicine, Clinic III - Hematology, Oncology, Palliative Medicine, Rostock University Medical Center, University of Rostock, Rostock, Germany.
Jana Vanessa SchefflerDepartment of Medicine, Clinic III - Hematology, Oncology, Palliative Medicine, Rostock University Medical Center, University of Rostock, Rostock, Germany.
Philipp KapsDepartment of Medicine, Clinic III - Hematology, Oncology, Palliative Medicine, Rostock University Medical Center, University of Rostock, Rostock, Germany.
Anne HieltscherDepartment of Medicine, Clinic III - Hematology, Oncology, Palliative Medicine, Rostock University Medical Center, University of Rostock, Rostock, Germany.
Björn SchneiderInstitute of Pathology, Rostock University Medical Center, University of Rostock, Rostock, Germany.
Daniel DubinskiDepartment of Neurosurgery, Rostock University Medical Center, University of Rostock, Rostock, Germany.
Florian GesslerDepartment of Neurosurgery, Rostock University Medical Center, University of Rostock, Rostock, Germany.
Thomas M FreimanDepartment of Neurosurgery, Rostock University Medical Center, University of Rostock, Rostock, Germany.
Felix WittigInstitute of Pharmacology and Toxicology, Rostock University Medical Center, University of Rostock, Rostock, Germany.
Sascha Troschke-MeurerDepartment of Pediatric Oncology and Hematology, University Medicine Greifswald, Greifswald, Germany.
Wendy Bergmann-EwertCore Facility for Cell Sorting & Cell Analysis, Rostock University Medical Center, University of Rostock, Rostock, Germany.
Susanne StaehlkeInstitute of Cell Biology, University Medical Center Rostock, Rostock, Germany.
Lars BoeckmannClinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, Rostock, Germany.
Philipp-Kjell FichtClinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, Rostock, Germany.
Christian PolleyDepartment of Microfluidics, Faculty of Mechanical Engineering and Marine Technology, University of Rostock, Rostock, Germany.
Christian JunghanssDepartment of Medicine, Clinic III - Hematology, Oncology, Palliative Medicine, Rostock University Medical Center, University of Rostock, Rostock, Germany.
Burkhard HinzInstitute of Pharmacology and Toxicology, Rostock University Medical Center, University of Rostock, Rostock, Germany.
Claudia MaletzkiDepartment of Medicine, Clinic III - Hematology, Oncology, Palliative Medicine, Rostock University Medical Center, University of Rostock, Rostock, Germany.ORCID https://orcid.org/0000-0002-8389-8439

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40836584
PMCPMC12367859

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.