Evidence map›Paper›PMID 40836511›Full record

ArticleHead & neck2026

Nasopharyngeal Endoscopic Resection Extended to the Internal Carotid Artery (Type 4): Technical Notes, Indications, and Outcomes.

Francesco Boaria, Alessandro Vinciguerra, Stefano Taboni, Martina Conti, Paola Costantino, Vittorio Rampinelli, Marco Valentini, Francesca Gennarini, Benjamin Verillaud, Elisabetta Zanoletti and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Head & neck, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Francesco BoariaOtorhinolaryngology and Skull Base Center, AP-HP, Hospital Lariboisière, Paris, France.
Alessandro VinciguerraOtorhinolaryngology and Skull Base Center, AP-HP, Hospital Lariboisière, Paris, France.
Stefano TaboniSection of Otorhinolaryngology-Head and Neck Surgery, Department of Neuroscience, University of Padua, Padua, Italy.
Martina ContiSection of Otorhinolaryngology-Head and Neck Surgery, Department of Neuroscience, University of Padua, Padua, Italy.
Paola CostantinoSection of Otorhinolaryngology-Head and Neck Surgery, Department of Neuroscience, University of Padua, Padua, Italy.
Vittorio RampinelliUnit of Otorhinolaryngology-Head and Neck Surgery, University of Brescia, Brescia, Italy.ORCID 0000-0002-0901-6266
Marco ValentiniDivision of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.
Francesca GennariniUnit of Otorhinolaryngology-Head and Neck Surgery, University of Brescia, Brescia, Italy.
Benjamin VerillaudOtorhinolaryngology and Skull Base Center, AP-HP, Hospital Lariboisière, Paris, France.
Elisabetta ZanolettiSection of Otorhinolaryngology-Head and Neck Surgery, Department of Neuroscience, University of Padua, Padua, Italy.
Davide MattavelliUnit of Otorhinolaryngology-Head and Neck Surgery, University of Brescia, Brescia, Italy.
Alberto SchreiberUnit of Otorhinolaryngology-Head and Neck Surgery, University of Brescia, Brescia, Italy.
Mario Turri-ZanoniUnit of Otorhinolaryngology-Head and Neck Surgery, University of Brescia, Brescia, Italy.
Alberto Daniele ArosioDivision of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.
Piergiorgio GaudiosoSection of Otorhinolaryngology-Head and Neck Surgery, Department of Neuroscience, University of Padua, Padua, Italy.
Paolo BattagliaDivision of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.
Maurizio BignamiDivision of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.
Paolo CastelnuovoDivision of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.
Philippe HermanOtorhinolaryngology and Skull Base Center, AP-HP, Hospital Lariboisière, Paris, France.
Piero NicolaiSection of Otorhinolaryngology-Head and Neck Surgery, Department of Neuroscience, University of Padua, Padua, Italy.
Marco FerrariSection of Otorhinolaryngology-Head and Neck Surgery, Department of Neuroscience, University of Padua, Padua, Italy.ORCID 0000-0002-4023-0121

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndoscopic surgical approaches for nasopharyngeal malignancies, including recurrent nasopharyngeal carcinoma (rNPC) and nasopharyngeal salivary gland tumors (NSGT), have seen significant development over the last decades. Our groups have expanded the classification of nasopharyngeal endoscopic resections (NER) from type 1 to 3 to incorporate internal carotid artery (ICA)-including ablations. The aim of this work is to describe the surgical technique, indications, and preliminary oncological outcomes of NER extended to ICA, proposing it as type 4 NER. METHODOLOGY: Consecutive patients affected by nasopharyngeal malignancies and treated with NER type 4 were included. Data on patient-, disease-, and treatment-related factors were collected. Adverse events were classified from G1 to G5 according to the Common Terminology Criteria for Adverse Events. Preliminary survival outcomes were measured. A detailed description of the surgical steps of NER type 4 was reported.

resultsA total of 13 patients were included: 7 NPC and 6 non-NPC, of which 4 were primary adenoid cystic carcinoma (ACC), 1 was recurrent ACC, and 1 was polymorphous adenocarcinoma. After a median follow-up of 34.7 months, 5 patients had a local recurrence during follow-up after a median of 17.3 months, one of which died at 10.3 months after surgery. The cumulative ≥ G3 adverse event rate was 61.5%. No major complications directly associated with ICA occlusion were reported.

conclusionsNER type 4 is a potential treatment alternative to (re)irradiation in highly selected patients with nasopharyngeal malignancies involving/abutting the ICA. The results reported should be considered preliminary; a novel description of the technique is provided.

Indexed as

Carcinoma, Adenoid CysticCarotid Artery, InternalEndoscopyNasopharyngeal NeoplasmsAdultAgedFemaleHumansMaleMiddle AgedNasopharyngeal CarcinomaNeoplasm Recurrence, LocalRetrospective StudiesTreatment Outcome

Identifiers

PMID40836511
PMCPMC12703580

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.