Evidence map›Paper›PMID 40836500›Full record

ArticleThe FEBS journal2026

Structural insights for enhanced ROS detoxification of eKatE, a recently identified catalase in atypical E. coli.

Eunhee Koh, Youngki Yoo, Mi Young Yoon, Myung Kyung Choi, Uijin Kim, Jun Bae Park, Sang Sun Yoon, Hyun-Soo Cho

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Article in The FEBS journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Eunhee KohInstitute for Geometry, Seoul National University, Seoul, Korea.ORCID 0000-0002-0901-6303
Youngki YooDepartment of Systems Biology, Yonsei University, Seoul, Korea.
Mi Young YoonDepartment of Microbiology, Yonsei University College of Medicine, Seoul, Korea.
Myung Kyung ChoiDepartment of Systems Biology, Yonsei University, Seoul, Korea.
Uijin KimDepartment of Systems Biology, Yonsei University, Seoul, Korea.
Jun Bae ParkDepartment of Systems Biology, Yonsei University, Seoul, Korea.
Sang Sun YoonDepartment of Microbiology, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0002-4103-1546
Hyun-Soo ChoDepartment of Systems Biology, Yonsei University, Seoul, Korea.ORCID 0000-0003-4067-4715

Funding

Korea National Institute of Health 2024-ER2107-01National Research Foundation of Korea 2019R1A6A1A03032869National Research Foundation of Korea 2022M3A9F3017506National Research Foundation of Korea NRF-2021M3A9I2080490National Research Foundation of Korea NRF-2021R1A2C3010506National Research Foundation of Korea RS-2024-00351254
6 · The paper itself

Abstract

Catalase is a crucial enzyme that protects organisms from reactive oxygen species (ROS)-induced oxidative stress. eKatE, a recently identified catalase variant in commensal Escherichia coli (E. coli), significantly contributes to infectious diseases and inflammatory bowel disease (IBD). Here, we enhanced the ROS detoxification capacity of eKatE, distinguishing it from the typical E. coli catalase KatE. eKatE forms a tetramer with a well-folded N-terminal arm and a dual conformation of the long R173

Indexed as

CatalaseEscherichia coliEscherichia coli ProteinsReactive Oxygen SpeciesHydrogen PeroxideModels, MolecularProtein ConformationCatalaseEscherichia coli ProteinsHydrogen PeroxideReactive Oxygen SpeciescatalaseeKatEinflammatory bowel diseaseoxidative stress

Identifiers

PMID40836500
PMCPMC12797018

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.