Evidence map›Paper›PMID 40836163›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Retrospective study on endonasal endoscopic management of cerebrospinal fluid rhinorrhea using pedicled nasal mucosal flap.

Nongping Zhong, Wenxuan Zhu, Li Shen, Jing Ye, Qing Luo

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

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5 authors.

Nongping Zhong *Department of Otorhinolaryngology Head and Neck Surgery, The first affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Wenxuan Zhu *Department of Otorhinolaryngology Head and Neck Surgery, The first affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Li ShenDepartment of Otorhinolaryngology Head and Neck Surgery, The first affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Jing YeDepartment of Otorhinolaryngology Head and Neck Surgery, The first affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Qing LuoDepartment of Otorhinolaryngology Head and Neck Surgery, The first affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China. luoq@ncu.edu.cn.ORCID http://orcid.org/0000-0002-3620-0106

Funding

Health Commission of Jiangxi Province 202130302Natural Science Foundation of Jiangxi Province 20212BAG70013
6 · The paper itself

Abstract

objectivesThe goal of this study was to analyze the surgical efficacy and application value of using autologous materials (pedicled nasal mucosal flaps) as the main repair material for cerebrospinal fluid rhinorrhea under nasal endoscopy in our department in the past 5 years.

methodsA retrospective analysis was conducted on patients who underwent cerebrospinal fluid rhinorrhea repair at our department between 1st February 2019 to 28th February 2024. Preoperative nasal endoscopy, computed tomography (CT) and/or magnetic resonance imaging (MRI) was performed to determine the location of the leak.

resultsA total of 25 patients were included consisting of 11 males (44%) and 14 females (56%), with age range from 8 to 57 years (39.8 ± 12.64 years). 21 cases (84%) were spontaneous cerebrospinal fluid leaks and 4 cases (16%) were traumatic leaks. The most common intraoperative defect site was ethmoid sinus (36%), followed by the sphenoid sinus (32%). The materials used for repair included pedicled nasoseptal flap (68%), middle turbinate mucosal flap (54%), artificial dura mater (76%), and fat grafts (12%). No Postoperative complications were observed in any of the patients. Overall, successful primary repair was achieved in all 25 patients, with the majority of cases employing a multilayered reconstruction method (96%).

conclusionThe use of pedicled nasal mucosal flaps and artificial dura mater in the endoscopic repair of cerebrospinal fluid rhinorrhea displays excellent success rates.

Indexed as

Cerebrospinal Fluid RhinorrheaEndoscopyNasal MucosaNatural Orifice Endoscopic SurgerySurgical FlapsAdolescentAdultChildFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedRetrospective StudiesTomography, X-Ray ComputedTreatment OutcomeCerebrospinal fluid rhinorrheaMiddle turbinateNasal endoscopyNasal pedicled mucosal flapNasal septum

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.