Evidence map›Paper›PMID 40836103›Full record

ArticleCardiovascular and interventional radiology2025

Novel Biopsy Gun Impacts Biopsy Sample Quality and Quantity.

Laetitia Saccenti, Tabea Borde, Nicole A Varble, Lindsey Hazen, Ming Li, Michael Kassin, Ifechi Ukeh, Sandeep Gurram, Peter A Pinto, Ivane Bakhutashvili and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular and interventional radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Laetitia Saccenti *Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 20892, USA. Laetitia.saccenti@nih.gov.ORCID http://orcid.org/0000-0002-9765-0039
Tabea Borde *Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Nicole A VarbleCenter for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Lindsey HazenCenter for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Ming LiCenter for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Michael KassinCenter for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Ifechi UkehCenter for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Sandeep GurramUrologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Peter A PintoUrologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Ivane BakhutashviliCenter for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 20892, USA.
William F PritchardCenter for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 20892, USA.
John W KaranianCenter for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Bradford J WoodCenter for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 20892, USA.

Funding

Center for Interventional OncologyZIDBC011242 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WOOD, BRADFORD J · 2009 to 2025
$18.7M
Intramural NIH HHS ZID BC011242Intramural Research Program of the National Institutes of Health 1ZIDBC011242
6 · The paper itself

Abstract

purposeA biopsy gun featuring alternated serrated cutting edges was designed to improve core stability and tissue acquisition. This study aimed to assess the impact upon core biopsy tissue quantity and quality of a serrated core gun (SUREcore prime, Uro-1). MATERIALS AND

methods18G serrated core gun was compared with 18G conventional gun (Maxcore, Becton Dickinson), in both ex vivo (bovine liver, N = 30) and in vivo (swine liver and kidney, N = 24) models. Cores were assessed for weight, length, surface area, fragmentation, and solidity using digital pathology.

resultsThe serrated core gun produced cores with 16% higher median weight (6.60 g vs. 5.70 g, p < 0.001), 10% longer length (11.1 mm vs. 10.1 mm, p = 0.042), and 16% greater surface area (7.80mm

conclusionThe serrated-edge design may improve biopsy sample quality and quantity without increasing needle size or penetration depth, potentially reducing the need for repeated passes. Device research and innovations may further improve biopsy efficacy and outcomes and reduce complications.

Indexed as

KidneyLiverAnimalsBiopsy, Large-Core NeedleCattleEquipment DesignSwineBiopsyEquipment designInterventional radiologyLarge-core needlePrecision medicine

Identifiers

PMID40836103
PMCPMC12535938

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