Evidence map›Paper›PMID 40835977›Full record

ReviewNature reviews. Microbiology2025

Respiratory viral coinfections: interactions, mechanisms and clinical implications.

Pallavi Deol, Tanya A Miura

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pallavi DeolDepartment of Biological Sciences and Institute for Modeling Collaboration and Innovation, University of Idaho, Moscow, ID, USA.ORCID http://orcid.org/0000-0002-8903-5714
Tanya A MiuraDepartment of Biological Sciences and Institute for Modeling Collaboration and Innovation, University of Idaho, Moscow, ID, USA. tmiura@uidaho.edu.ORCID http://orcid.org/0000-0002-7289-4926

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many heterologous viruses that infect the respiratory tract co-circulate within human populations. With the advent of multiplex diagnostic tests for respiratory viruses, there is increased appreciation of viral coinfection within an individual host. Thus, it is important to understand the interactions between heterologous respiratory viruses at the levels of populations, hosts and cells, as well as the impact of these interactions on pathogen prevalence and disease severity. In this Review, we summarize studies that demonstrate antagonistic or synergistic interactions between respiratory viruses, resulting in altered viral prevalence in populations, replication in hosts and cells, and disease severity in clinical cases and animal models. Understanding these interactions at a mechanistic level will affect future strategies to prevent and treat respiratory viral infections.

Indexed as

CoinfectionRespiratory Tract InfectionsVirus DiseasesAnimalsHost-Pathogen InteractionsHumansVirus Replication

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.