Evidence map›Paper›PMID 40835963›Full record

Trial reportJournal of orthopaedic surgery and research2025

Isokinetic eccentric vs. concentric training for functional ankle instability: a randomized controlled trial.

Dunbing Huang, Wei Song, Yang Liu, Xiaohua Ke, Zhenhua Wu

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dunbing Huang *Encephalopathy and Rehabilitation Center, The Second Affiliated Hospital of Zhejiang Chinese Medical University, No. 318 Chaowang Road, Hangzhou, Zhejiang, 310005, China.
Wei Song *Department of Rehabilitation Medicine, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, 1279 Sanmen Road, Shanghai, 200434, China.
Yang LiuDepartment of Rehabilitation Medicine, Zhejiang Hospital, No. 12 Lingyin, Zhejiang, 310013, Hangzhou, China.
Xiaohua KeDepartment of Rehabilitation Medicine, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, 1279 Sanmen Road, Shanghai, 200434, China. kxh22@tongji.edu.cn.
Zhenhua WuEncephalopathy and Rehabilitation Center, The Second Affiliated Hospital of Zhejiang Chinese Medical University, No. 318 Chaowang Road, Hangzhou, Zhejiang, 310005, China. 458800977@qq.com.

Funding

the Research Launch Project of The Fourth People's Hospital Affiliated to Tongji University sykyqd08101the Zhejiang province science and Technology program of traditional Chinese medicine 2022ZA002
6 · The paper itself

Abstract

objectiveTo investigate the effects of a 12-week isokinetic eccentric training program on postural control and ankle muscle strength in individuals with functional ankle instability (FAI).

methodsIn this randomized controlled trial, 42 participants with unilateral FAI were randomly assigned to either an experimental group (n = 21), receiving isokinetic eccentric training, or a control group (n = 21), receiving isokinetic concentric training. Both groups trained three times per week for 12 weeks. One participant from each group dropped out during the intervention, resulting in 20 participants per group included in the final analysis. Primary outcomes included static and dynamic postural control assessed using the Pro-Kin 254P platform. Secondary outcomes were ankle dorsiflexion and eversion strength, as well as dorsiflexion/plantarflexion (D/P) and eversion/inversion (E/I) torque ratios measured with a Biodex System 4 Pro

resultsAfter 12 weeks, the experimental group demonstrated significantly greater improvements in postural control and ankle strength outcomes compared to the control group (p < 0.01). For dynamic postural control, the total offset index decreased by 23.8% in the eccentric group, showed a significant improvement with a very large effect size (Cohen's d = 2.06, 95% CI [1.29, 2.82], p < 0.001). Static postural control, measured by sway area, was reduced by 17.3% (Cohen's d = 0.81, 95% CI [0.16, 1.45], p = 0.015), while sway length did not reach statistical significance (Cohen's d = 0.55, 95% CI [-0.08, 1.18], p = 0.090). Regarding ankle strength, dorsiflexion relative peak torque (RPT) at 60°/s increased by 30.7% in the eccentric group (Cohen's d = - 0.79, 95% CI [-1.44, - 0.15], p = 0.016), while eversion RPT at 180°/s improved by 75.7% (Cohen's d = - 1.13, 95% CI [-1.79, - 0.46], p = 0.001). The D/P torque ratio at 180°/s exhibited a very large between-group difference (Cohen's d = - 2.18, 95% CI [-2.96, - 1.39], p < 0.001), and the E/I torque ratio at 60°/s demonstrated an extremely large effect size (Cohen's d = - 4.50, 95% CI [-5.67, - 3.34], p < 0.001).

conclusionIsokinetic eccentric training significantly enhances postural stability and ankle muscle strength in patients with FAI. These improvements in torque symmetry and balance support the inclusion of eccentric training as an effective rehabilitation strategy to reduce reinjury risk and restore neuromuscular function.

Indexed as

Ankle JointExercise TherapyJoint InstabilityResistance TrainingAdultFemaleHumansMaleMuscle StrengthPostural BalanceTreatment OutcomeYoung AdultDorsiflexionEversionFunctional ankle instabilityIsokinetic eccentric trainingIsokinetic muscle strengthPostural control

Identifiers

PMID40835963
PMCPMC12366329

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.