Evidence map›Paper›PMID 40835945›Full record

ArticleBMC chemistry2025

Selenium nanoparticle loaded on PVA/chitosan biofilm synthesized from orange peels: antimicrobial and antioxidant properties for plum preservation.

Hamza T O Abdelaziz, Eldin M Seif Mohamed, Samir K A Younis, Nada Ahmed, Mary N Michaeel, Samah H Abu-Hussien, Ashraf Bakry, Naglaa M Ebeed, Mohamed A Nasser, Mohamed K Abou El-Nasr and 4 more

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In one paragraph

Article in BMC chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hamza T O Abdelaziz *Biotechnology Program, Faculty of Agriculture, Ain Shams University, Cairo, 11241, Egypt.
Eldin M Seif Mohamed *Biotechnology Program, Faculty of Agriculture, Ain Shams University, Cairo, 11241, Egypt.
Samir K A Younis *Biotechnology Program, Faculty of Agriculture, Ain Shams University, Cairo, 11241, Egypt.
Nada Ahmed *Biotechnology Program, Faculty of Agriculture, Ain Shams University, Cairo, 11241, Egypt.
Mary N Michaeel *Biotechnology Program, Faculty of Agriculture, Ain Shams University, Cairo, 11241, Egypt.
Samah H Abu-HussienDepartment of Agricultural Microbiology, Faculty of Agriculture, Ain Shams University, Cairo, 11241, Egypt.
Ashraf BakryDepartment of Genetics, Faculty of Agriculture, Ain Shams University, Hadayek Shoubra, PO Box 68, Cairo, 11241, Egypt.
Naglaa M EbeedDepartment of Genetics, Faculty of Agriculture, Ain Shams University, Hadayek Shoubra, PO Box 68, Cairo, 11241, Egypt.
Mohamed A NasserDepartment of Horticulture, Faculty of Agriculture, Ain Shams University, Cairo, 11241, Egypt.
Mohamed K Abou El-NasrDepartment of Horticulture, Faculty of Agriculture, Ain Shams University, Cairo, 11241, Egypt.
Mahmoud A A AliDepartment of Horticulture, Faculty of Agriculture, Ain Shams University, Cairo, 11241, Egypt.
Bahaa HemdanWater Pollution Research Department, Environment and Climate Change Research Institute, National Research Centre, 33 El Buhouth Street, P.O. Box 12622, Giza, Egypt. bahaa_nrc@yahoo.com.
Mahmoud SalahDepartment of Environmental Agricultural Science, Faculty of Graduate Studies and Environmental Research, Ain Shams University, Cairo, 11566, Egypt.
Salwa M El-SayedDepartment of Biochemistry, Faculty of Agriculture, Ain Shams University, Cairo, 11241, Egypt. Salwa_sedeek@agr.asu.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the eco-friendly synthesis, characterization, and biological activity of selenium nanoparticles (SeNPs) incorporated into a polyvinyl alcohol/chitosan (PVA/CH) composite for antimicrobial, antioxidant, and food preservation applications. SeNPs were synthesized using orange peel extract as a reducing and stabilizing agent. Characterization through UV-Vis spectroscopy, FTIR, dynamic light scattering (DLS), TEM and zeta potential analysis confirmed the formation of stable, well-dispersed SeNPs. The antimicrobial activity of PVA/chitosan (PVA/CH) films incorporated with selenium nanoparticles (SeNPs) was evaluated against five pathogenic bacterial strains, showing a concentration-dependent enhancement, with the 1% SeNPs formulation achieving the highest inhibition zones across all tested pathogens. Se nanoparticles showed a more compact structure and excellent thermal and UV stability into PVA/CH-SeNPS film. Antioxidant potential was assessed using DPPH radical scavenging assays. The composites showed concentration-dependent free radical scavenging, with the highest activity observed at 1% SeNP concentration (IC50:45.2 µg/mL), closely approaching that of ascorbic acid (IC50: 38.6 µg/mL). HPLC analysis of orange peel extract identified high levels of rutin (546.46 mg/kg), quercetin (217.45 mg/kg), and chlorogenic acid (72.75 mg/kg), which likely contributed to the observed antioxidant properties. Cytotoxicity tests using Vero cells demonstrated high biocompatibility, with over 80% cell viability at all tested concentrations, confirming the composites’ potential for safe biomedical applications. Additionally, the use of PVA/CH-SeNP composites as an edible coating for Hollywood plum (Prunus domestica L. cv. Hollywood) was evaluated to extend postharvest storage. Fruits coated with 0.5% and 1% PVA/CH-SeNP showed significantly reduced weight loss (3.64% and 2.84%, respectively, compared to 6.91% in the control) and maintained higher firmness (7.20 N/cm² vs. 4.12 N/cm² in the control). The coatings also increased total soluble solids (TSS: 14.6°Brix), decreased acidity (0.936%), and enhanced L-ascorbic acid (19.86 mg/100 g) and anthocyanin content. These results highlight the potential of PVA/CH-SeNP composites as multifunctional biomaterials for antimicrobial, antioxidant, and food preservation applications. Future studies should explore their in vivo efficacy, long-term stability, and potential for large-scale applications.

Indexed as

Antimicrobial activityAntioxidant propertiesEdible coatingFood securityGreen synthertized SeNPSOrange peelsPVA/Chitosan composite

Identifiers

PMID40835945
PMCPMC12366351

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.