Evidence map›Paper›PMID 40835859›Full record

ArticleScientific reports2025

Context-dependent effects of carbon dioxide on cross-modal integration during mosquito flight.

Aya Kato-Namba, Kazumi Ohta, Takao Nakagawa, Hokto Kazama

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aya Kato-Namba *Human Health Care Research, Kao Corporation, 2-1-3 Bunka, Sumida-ku, Tokyo, 131- 8501, Japan. katou.aya2@kao.com.
Kazumi Ohta *RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, 351-0198, Saitama, Japan.
Takao NakagawaHuman Health Care Research, Kao Corporation, 2-1-3 Bunka, Sumida-ku, Tokyo, 131- 8501, Japan.
Hokto KazamaRIKEN Center for Brain Science, 2-1 Hirosawa, Wako, 351-0198, Saitama, Japan. hokto.kazama@riken.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To navigate the environment and search for hosts, mosquitoes utilize multiple sensory cues including carbon dioxide (CO₂), visual, olfactory, and humidity cues. However, how mosquitoes shape their behavior by integrating these cues is poorly understood. Here we monitored the flight maneuvers of Aedes albopictus in a virtual reality environment where sensory cues were presented in open- or closed-loop. We found that CO₂ enhances optomotor responses to wide-field motion stimuli provided with various angular speeds and contrasts. Furthermore, CO₂ allowed more accurate tracking of a low contrast, visual object whose position was updated in closed-loop. We also found that olfactory preference is bidirectionally modulated by CO₂ depending on the value of odors: CO₂ enhances attraction to host odors whereas it enhances aversion to a repellent. This olfactory enhancement was further contingent on the humidity level. Together, our results highlight the context-dependent impact of CO₂ on cross-modal integration in mosquitoes.

Indexed as

AedesCarbon DioxideFlight, AnimalAnimalsCuesFemaleHumidityOdorantsSmellCarbon Dioxide

Identifiers

PMID40835859
PMCPMC12368251

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.