Evidence map›Paper›PMID 40835776›Full record

Observational studyEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Comparison of quality of life between operated and non-operated adults with painful degenerative scoliosis: a 2-year prospective multicentered observational study.

Mikael Finoco, Mourad Ould-Slimane, Laura Marie-Hardy, Mathieu De Seze, Emmanuelle Chaleat-Valayer, Isabelle Courtois, Benjamin Bouyer, Yann-Philippe Charles, François Rannou, Pierre Guigui and 2 more

Abstract readObservational StudyMulticenter StudyComparative Study
PubMed Publisher
In one paragraph

Observational study in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mikael FinocoOrthopaedic Surgery Department, Hôpital Européen Georges Pompidou, AP-HP, 20 Rue Leblanc, Paris, 75015, France. mikael.finoco@gmail.com.ORCID 0000-0003-1525-2967
Mourad Ould-SlimaneOrthopaedic Surgery Department, Spine Unit, Rouen University Hospital, Institut Rouennais du Rachis, CHU de Rouen, 1, Rue de Germont, Rouen, 76000, France.
Laura Marie-HardyOrthopaedic Surgery Unit, Hôpital Pitié Salpetrière, AP-HP, 47-83 Boulevard de l'Hôpital, Paris, 75013, France.
Mathieu De SezeOrthopaedic and Sport Medicine Unit, Université de Bordeaux, Bordeaux University Hospital, C.H.U Tripode Pellegrin, Place Amélie Raba Léon, Bordeaux, 33076, France.
Emmanuelle Chaleat-ValayerService de Rééducation et de Réadaptation de l'Appareil Locomoteur et des Pathologies du Rachis. Centre Médico-Chirurgical Réadaptation des Massues- Croix-Rouge Française, 92 Rue Dr Edmond Locard, Lyon, 69005, France.
Isabelle CourtoisService de Rééducation et de Réadaptation de l'Appareil Locomoteur et des Pathologies du Rachis. Hôpital Bellevue, 25 Boulevard Pasteur, Saint Etienne, 42100, France.
Benjamin BouyerDepartment of Spinal Surgery, Université de Bordeaux, Bordeaux University Hospital Unit 1, C.H.U Tripode Pellegrin, Place Amélie Raba Léon, Bordeaux, 33076, France.
Yann-Philippe CharlesService de Chirurgie du Rachis, Hôpitaux Universitaires de Strasbourg, Université de Strasbourg, 1, Avenue Molière, Strasbourg, 67200, France.
François RannouFaculté de Santé, Université Paris Cité, UFR de Médecine, Paris, 75006, France.
Pierre GuiguiOrthopaedic Surgery Department, Hôpital Européen Georges Pompidou, AP-HP, 20 Rue Leblanc, Paris, 75015, France.
Christelle NguyenFaculté de Santé, Université Paris Cité, UFR de Médecine, Paris, 75006, France.
Emmanuelle FerreroOrthopaedic Surgery Department, Hôpital Européen Georges Pompidou, AP-HP, 20 Rue Leblanc, Paris, 75015, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAdult scoliosis can lead to severe impairment of quality of life. Conservative and surgical treatment are two available options to improve quality of life. Surgical treatment is effective to correct severe deformations but with significant morbidity. The comparison of the two treatments remains heterogeneous in the literature with significant cross-over to surgical treatment. The objective of the study was to compare health-related quality of life between operated and non-operated adults with painful degenerative scoliosis at 2-year follow-up.

methodsAll patients aged between 50 to 80 years with lumbar scoliosis were prospectively included in a 2-year prospective multicentered observational study with 12 French tertiary care centers. Two groups were defined: operated group and non-operated group. Demographics, radiological parameters, surgical parameters and complications were collected. 4 clinical scores were self-reported at baseline at 1- and at 2-year follow-up and included SF-12, VAS, SRS 30 and ODI.

resultsA total of 181 patients were included. Pre-treatment physical and mental components of SF-12 score were not significantly different between operated and non-operated groups with respective values of 31.2 ± 6.9 vs 34 ± 9.4 (p > 0.05) and 41.6 ± 9.5 vs 43.2 ± 13.9 (p > 0.05). Post-treatment SF-12 PCS and MCS score were not significantly different between operated and non-operated groups with respective values of 42 ± 8 vs 42 ± 9 (p = 0.65) and 46 ± 11 vs 49 ± 11 (p = 0.08). At 2 years FU, for SF-12 PCS, 41 more patients (52.5%) in operated group achieved the PASS threshold compared with pre-operative status and 19 more patients (57.6%) in non-operated group (p = 0.71). For SF-12 MCS, 40 more patients (50%) in operated group achieved the PASS threshold compared with pre-treatment status and 6 more patients (18%) in non-operated group (p = 0.002). VAS, ODI and SRS were not significantly different between the 2 groups, except function component of SRS which was higher in non-operated group (p = 0.02). Main lumbar Cobb angle correction was significantly better in operated group than in non-operated group with respective correction values of 26 ± 17° vs 4 ± 10° (p = 0.0001).

conclusionResults of our study show that both operative and non-operative treatments are associated with clinical improvement at 2-year-follow-up in adults with painful degenerative scoliosis. SF-12 PCS scores improved and did not differ between operated and non-operated groups, while SF-12 MCS scores improved and were better in operative group at 2 years. As expected, surgical treatment was effective in correcting sagittal and frontal balance.

Indexed as

Quality of LifeScoliosisAgedAged, 80 and overFemaleHumansLumbar VertebraeMaleMiddle AgedProspective StudiesSpinal FusionTreatment OutcomeAdult scoliosisClinical scoresConservative treatmentHealth-related quality of lifeODISF-12Surgical treatment

Identifiers

PMID40835776

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.