ArticleSurgical endoscopy2025
Predictors of clinical failure after stenting for malignant esophageal stricture: a single-institution retrospective analysis.
Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Predictors of dysfunction in fully versus partially covered self-expanding metal stents for malignant esophageal strictures: a 10-year multicenter study.BMC gastroenterology · 2026Observational
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe placement of an esophageal self-expandable metal stent (SEMS) is an effective palliative treatment for inoperable malignant esophageal stricture. However, despite successful stent placement, some patients continue to experience persistent dysphagia. We aimed to evaluate the predictive factors of clinical outcomes after endoscopic SEMS placement for malignant esophageal stricture.
methodsBetween November 2008 and January 2024, 220 patients who underwent successful endoscopic SEMS placement for malignant esophageal stricture in an academic referral center were included in the analysis. We retrospectively evaluated variables associated with clinical outcomes following successful SEMS placement using univariate and multivariate analyses.
resultsThe clinical success rate of endoscopic SEMS placement was 77.7%. The mean age of the patients was 78 years with a male predominance (82.7%). The most common causes were squamous cell esophageal carcinoma (59.5%) and gastric cancer (25.9%). Endoscopic passage was not achievable in 31.4% of patients. A poor performance status (Eastern Cooperative Oncology Group [ECOG] performance status 2-3) was observed in 42.3% of patients, severe dysphagia (water intake only) in 67.3%, and carcinomatosis peritonei in 11.8% of patients. Narcotics were required for analgesia after stenting in 37.7% of patients. Multivariate analysis performed with significant variables determined using univariate analysis showed that need for narcotics after stenting (p = 0.020, odds ratio [OR] 2.768, 95% confidence interval [CI] 1.178-6.504), presence of carcinomatosis peritonei (p = 0.037, OR 2.992, CI 1.067-8.391), and poor performance status (ECOG 2 ~ 3) (p = 0.001, OR 5.076, CI 2.024-12.658) were significant predictive factors of clinical failure after stenting.
conclusionThe need for narcotics after SEMS placement, presence of carcinomatosis peritonei, and poor performance status (ECOG 2-3) are significantly associated with clinical failure of palliative SEMS placement.
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