Evidence map›Paper›PMID 40835679›Full record

ArticleScientific reports2025

Detection of spinal action potentials with subdural electrodes in freely moving rodents.

Brittany Hazelgrove, Bruce Harland, Salvador Lopez, Maria Asplund, Leo K Cheng, Darren Svirskis, Brad Raos

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Brittany HazelgroveUniversity of Auckland, Auckland, New Zealand.
Bruce HarlandUniversity of Auckland, Auckland, New Zealand.
Salvador LopezUniversity of Auckland, Auckland, New Zealand.
Maria AsplundChalmers University of Technology, Gothenburg, Sweden.
Leo K ChengUniversity of Auckland, Auckland, New Zealand.
Darren SvirskisUniversity of Auckland, Auckland, New Zealand.
Brad RaosUniversity of Auckland, Auckland, New Zealand. b.raos@auckland.ac.nz.

Funding

CatWalk Spinal Cord Injury Research Trust Cure ProgrammeHealth Research Council of New Zealand 24/184/AUniversity of Auckland Doctoral ScholarshipU.S. Department of Defense HT9425-23-1-0492
6 · The paper itself

Abstract

Recording directly from the spinal cord surface in freely behaving animals provides a promising means to investigate spinal electrophysiology, typically examined in stimulation experiments or during controlled behaviour. In a two-week experiment, we extract high-frequency spiking activity in control and spinal cord injured rats during freely behaving, open-field recording sessions. Electrical signals were recorded using sputtered iridium oxide (SIROF) electrodes on a polyimide-based, flexible probe surgically inserted beneath the dura of the spinal column, with electrodes in direct contact with the thoracic and lumbar spinal cord. The propagation of neural spikes was investigated following bandpass filtering in the high-frequency range (300-3000 Hz). A large, slow-travelling ascending and descending cluster was identified (< 15 ms

Indexed as

Action PotentialsSpinal CordSpinal Cord InjuriesAnimalsElectrodesElectrodes, ImplantedFemaleRatsRats, Sprague-DawleyAction potentialsBioelectronicsNeural activityNeural implantsPropagation

Identifiers

PMID40835679
PMCPMC12368248

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.