Evidence map›Paper›PMID 40835669›Full record

ArticleScientific reports2025

Computational optimization of 3D printed bone scaffolds using orthogonal array-driven FEA and neural network modeling.

Amulya Shetty, Aamirah Fathima, B Anika, Raviraj Shetty, Vinyas, J P Supriya, Adithya Hegde

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. How Emerging Nanomaterials are Effective in Bone Regeneration?International journal of nanomedicine · 2026
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amulya ShettyFather Muller Medical College, Mangalore, Karnataka, 575002, India.
Aamirah FathimaFather Muller Medical College, Mangalore, Karnataka, 575002, India.
B AnikaFather Muller Medical College, Mangalore, Karnataka, 575002, India.
Raviraj ShettyDepartment of Mechanical and Industrial Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, 576104, India. rr.shetty@manipal.edu.
VinyasDepartment of Mechanical and Industrial Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, 576104, India. vinyas.shetty@manipal.edu.
J P SupriyaDepartment of Mechanical and Industrial Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, 576104, India.
Adithya HegdeDepartment of Mechanical and Industrial Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, 576104, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Today, orthopedic surgeons have been continuously focusing on bone tissue engineering for regenerating damaged bone through the use of biomimetic scaffolds and innovative materials. Hence, this study presents a comprehensive investigation into the optimization of PLA + 3D printed lattice scaffolds for bone tissue engineering applications, emphasizing the role of geometric configuration and processing parameters on mechanical performance. Three distinct lattice geometries such as Lidinoid, Diamond, and Gyroid were developed with varying wall thicknesses (1.0 mm, 1.5 mm, and 2.0 mm) and subjected to compressive loads of 3 kN, 6 kN, and 9 kN. A Taguchi L

Indexed as

Bone and BonesNeural Networks, ComputerPrinting, Three-DimensionalTissue EngineeringTissue ScaffoldsFinite Element AnalysisHumansStress, MechanicalAdditively manufactured scaffoldsArtificial neural networkBone tissue engineeringFinite element analysisMechanical characterizationMicrostructural analysisSoft computing techniquesTaguchi design of experiments

Identifiers

PMID40835669
PMCPMC12368192

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.