Evidence map›Paper›PMID 40835612›Full record

ArticleNature communications2025

Deep learning approach for screening neonatal cerebral lesions on ultrasound in China.

Zhouqin Lin, Haoming Zhang, Xingxing Duan, Yan Bai, Jian Wang, Qianhong Liang, Jingran Zhou, Fusui Xie, Zhen Shentu, Ruobing Huang and 6 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Zhouqin Lin *Department of Medical Ultrasonics, Shenzhen Children's Hospital, Shenzhen, PR China.ORCID http://orcid.org/0000-0001-7059-6899
Haoming Zhang *School of Biomedical Engineering, Shenzhen University, Shenzhen, PR China.ORCID http://orcid.org/0009-0008-6442-7739
Xingxing Duan *Department of Ultrasonography, Changsha Hospital for Maternal and Child Health Care, Changsha, PR China.ORCID http://orcid.org/0000-0002-4094-5127
Yan Bai *Sichuan Provincial Women's and Children's Hospital/The Affiliated Women's and Children's Hospital of Chengdu Medical College, Chengdu, PR China.
Jian WangSchool of Biomedical Engineering, Shenzhen University, Shenzhen, PR China.ORCID http://orcid.org/0000-0003-1962-0341
Qianhong LiangPanyu Maternal and Child Care Service Centre of Guangzhou, Guangzhou, PR China.
Jingran ZhouDepartment of Medical Ultrasonics, Shenzhen Children's Hospital, Shenzhen, PR China.
Fusui XieDepartment of Medical Ultrasonics, Shenzhen Children's Hospital, Shenzhen, PR China.
Zhen ShentuShenzhen Pediatrics Institute of Shantou University Medical College, Shenzhen, PR China.
Ruobing HuangSchool of Biomedical Engineering, Shenzhen University, Shenzhen, PR China.
Yayan ChenUltrasound Department of Longhua District Maternal and Child Healthcare Hospital, Shenzhen, PR China.
Hongkui YuDepartment of ultrasound, Shenzhen Baoan Women's and Children's Hospital, Shenzhen, PR China.
Zongjie WengDepartment of Medical Ultrasonics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, PR China.
Dong NiMedical Ultrasound Image Computing (MUSIC) Lab, School of Biomedical Engineering, Medical School, Shenzhen University, Shenzhen, PR China. nidong@szu.edu.cn.ORCID http://orcid.org/0000-0002-9146-6003
Lei LiuDepartment of Medical Ultrasonics, Shenzhen Children's Hospital, Shenzhen, PR China. szliulei19@163.com.
Luyao ZhouDepartment of Medical Ultrasonics, Shenzhen Children's Hospital, Shenzhen, PR China. zhouly@email.szu.edu.cn.ORCID http://orcid.org/0000-0002-1828-0878

Funding

National Natural Science Foundation of China (National Science Foundation of China) No. 12326619National Natural Science Foundation of China (National Science Foundation of China) NO: 82271996
6 · The paper itself

Abstract

Timely and accurate diagnosis of severe neonatal cerebral lesions is critical for preventing long-term neurological damage and addressing life-threatening conditions. Cranial ultrasound is the primary screening tool, but the process is time-consuming and reliant on operator's proficiency. In this study, a deep-learning powered neonatal cerebral lesions screening system capable of automatically extracting standard views from cranial ultrasound videos and identifying cases with severe cerebral lesions is developed based on 8,757 neonatal cranial ultrasound images. The system demonstrates an area under the curve of 0.982 and 0.944, with sensitivities of 0.875 and 0.962 on internal and external video datasets, respectively. Furthermore, the system outperforms junior radiologists and performs on par with mid-level radiologists, with 55.11% faster examination efficiency. In conclusion, the developed system can automatically extract standard views and make correct diagnosis with efficiency from cranial ultrasound videos and might be useful to deploy in multiple application scenarios.

Indexed as

BrainDeep LearningNeonatal ScreeningChinaFemaleHumansInfant, NewbornMaleUltrasonography

Identifiers

PMID40835612
PMCPMC12368173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.