Evidence map›Paper›PMID 40835467›Full record

ArticleInternal medicine (Tokyo, Japan)2026

Recurrent Hemorrhagic Stroke in a Patient with Neurosarcoidosis.

Tatsuya Saito, Hideaki Onda, Atsuhiko Shindo, Takanori Hata, Yuto Morishima, Yuki Nakamura, Hiroaki Murata, Takamura Nagasaka, Toyoaki Shinohara, Susumu Matsukuma and 2 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tatsuya SaitoDepartment of Neurology, University of Yamanashi, Japan.
Hideaki OndaDivision of Neurosurgery, Kofu Neurosurgical Hospital, Japan.
Atsuhiko ShindoDepartment of Neurology, University of Yamanashi, Japan.
Takanori HataDepartment of Neurology, University of Yamanashi, Japan.
Yuto MorishimaDepartment of Neurology, University of Yamanashi, Japan.
Yuki NakamuraDepartment of Neurology, University of Yamanashi, Japan.
Hiroaki MurataDepartment of Neurology, University of Yamanashi, Japan.
Takamura NagasakaDivision of Neurology, Kofu Neurosurgical Hospital, Japan.
Toyoaki ShinoharaDivision of Neurosurgery, Kofu Neurosurgical Hospital, Japan.
Susumu MatsukumaDepartment of Pathology and Laboratory Medicine, National Defense Medical College, Japan.
Kazumasa ShindoDepartment of Neurology, University of Yamanashi, Japan.
Yuji UenoDepartment of Neurology, University of Yamanashi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 45-year-old Japanese woman had sudden-onset subarachnoid hemorrhage and subsequently developed recurrent intracerebral hemorrhages and multiple infarctions in the left and right cerebral hemispheres, respectively. Angiotensin-converting enzyme (ACE) levels in the cerebrospinal fluid (CSF) were elevated, and a pathological examination of brain biopsy samples demonstrated multinucleated giant cell infiltration and epithelial granuloma formation in thickened pial vessel walls. After treatment with intravascular methylprednisolone 1,000 mg for 3 days, followed by oral prednisolone, she had no recurrence of cerebrovascular events. Although systemic involvement was lacking, isolated neurosarcoidosis was diagnosed based on increased ACE levels in the CSF and pathological findings.

Indexed as

Central Nervous System DiseasesHemorrhagic StrokeSarcoidosisSubarachnoid HemorrhageFemaleHumansMethylprednisoloneMiddle AgedPeptidyl-Dipeptidase ARecurrenceMethylprednisolonePeptidyl-Dipeptidase Ahemorrhagic strokeintracranial hemorrhageneurosarcoidosisrecurrencesubarachnoid hemorrhage

Identifiers

PMID40835467
PMCPMC13070597

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.