Evidence map›Paper›PMID 40835396›Full record

ReviewEuropean respiratory review : an official journal of the European Respiratory Society2025

Comparative analysis of guidelines and recommendations for sedation during flexible bronchoscopy: a narrative review.

Longfei Wang, Mengyan Wang, Rong Xu, Jianjun Li, Yunfei Cao, FuCheng Ji

Abstract readReview
In one paragraph

Review in European respiratory review : an official journal of the European Respiratory Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Longfei WangDepartment of Anesthesiology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, Shandong, P.R. China.ORCID https://orcid.org/0000-0002-3148-0866
Mengyan WangDepartment of Anesthesiology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, Shandong, P.R. China.ORCID https://orcid.org/0009-0001-4120-8049
Rong XuDepartment of Anesthesiology, Beilun District People's Hospital of Ningbo, Ningbo, Zhejiang, P.R. China.
Jianjun LiDepartment of Anesthesiology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, Shandong, P.R. China.ORCID https://orcid.org/0000-0003-1304-3969
Yunfei CaoDepartment of Anesthesiology, Beilun District People's Hospital of Ningbo, Ningbo, Zhejiang, P.R. China.ORCID https://orcid.org/0000-0002-0698-8537
FuCheng JiDepartment of Anesthesiology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, Shandong, P.R. China 18561810385@163.com.ORCID https://orcid.org/0009-0006-2381-4922

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFlexible bronchoscopy is an essential, invasive procedure used in clinical practice for diagnosing and treating bronchial, pulmonary, thoracic and other diseases. Due to concerns about the potential for intense stimulation during flexible bronchoscopy operations, sedation is recommended by most countries and regions for all patients without contraindications. However, the use of sedative and analgesic substances for sedation during flexible bronchoscopy may result in respiratory depression, potentially leading to hypoxaemia and/or hypercapnia. Considering these side-effects and associated risks, some countries and regions do not recommend this approach.

objectiveThis review aims to compare and analyse differences between currently published guidelines on sedation during flexible bronchoscopy and expert consensus in five key aspects: the necessity of sedation, qualifications of the person in charge of sedation, selection of sedative or anaesthetic drugs, sedation depth and perioperative monitoring, and oxygen supplementation and remedies.

conclusionsUndeniably, more attention and clinical evidence are needed to address the controversies and disputes existing among currently published guidelines on sedation during flexible bronchoscopy or expert consensus. Furthermore, international cooperation is necessary to establish standard international training and practice guidelines for sedation during flexible bronchoscopy.

Indexed as

BronchoscopyHypnotics and SedativesPractice Guidelines as TopicProcedural SedationConsensusHumansRisk FactorsHypnotics and Sedatives

Identifiers

PMID40835396
PMCPMC12365665

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.