Evidence map›Paper›PMID 40835394›Full record

SynthesisEuropean respiratory review : an official journal of the European Respiratory Society2025

Recovery of lung function during the first year after COVID-19: a systematic review and meta-analysis.

Katrine K Iversen, Marcus Sebastian Roldgaard, Ioannis Konstantinidis, Magnus Søltoft Lindhardt, Magnus G Ahlström, Alison Morris, Andreas Ronit, Thomas Benfield

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in European respiratory review : an official journal of the European Respiratory Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Katrine K IversenDepartment of Infectious Diseases, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark katrine.kjaer.iversen@regionh.dk.
Marcus Sebastian RoldgaardDepartment of Infectious Diseases, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark.
Ioannis KonstantinidisDivision of Pulmonary, Allergy, Critical Care, and Sleep Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Magnus Søltoft LindhardtDepartment of Infectious Diseases, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark.
Magnus G AhlströmDepartment of Clinical Microbiology, Copenhagen University Hospital-Hvidovre, Copenhagen, Denmark.
Alison MorrisDivision of Pulmonary, Allergy, Critical Care, and Sleep Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Andreas RonitDepartment of Infectious Diseases, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark.
Thomas BenfieldDepartment of Infectious Diseases, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark.

Funding

Risk factors for chronic obstructive pulmonary disease exacerbations, quality of care, and outcomes in people with HIVK08HL169023 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Ioannis Konstantinidis · 2023 to 2026
$653k
NHLBI NIH HHS K08 HL169023
6 · The paper itself

Abstract

backgroundSeveral studies have reported lung function impairment following COVID-19. Less is known about the subsequent recovery. RESEARCH QUESTION: What is the recovery in lung function after COVID-19 during the first year after infection?

methodsWe conducted a systematic review and meta-analysis of studies that monitored individuals' lung function from the time of infection to at least 1 year after infection. Primary outcomes were change in percent predicted forced expiratory volumes in 1 s (FEV

resultsWe included 23 studies (n=3347 participants). 20 (86.9%) studies had their first follow-up 3 months after infection and 21 (91.3%) had their second follow-up 12 months after infection. The MDs between the second and first follow-up visits of FEV

interpretationRecovery in lung function was evident during the first year after COVID-19, with the largest improvement in patients with the most severe infection. Further follow-up and large-scale studies are warranted to establish recovery trajectories of COVID-19 and other respiratory infections to identify patient subgroups needing additional follow-up to ascertain modifiable factors influencing pulmonary recovery.

Indexed as

COVID-19LungForced Expiratory VolumeHumansPulmonary Diffusing CapacityRecovery of FunctionRespiratory Function TestsSARS-CoV-2Time FactorsVital Capacity

Identifiers

PMID40835394
PMCPMC12365666

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.