Evidence map›Paper›PMID 40834326›Full record

ArticleJCO precision oncology2025

Aqueous Humor Liquid Biopsy Identifies Murine Double Minute 4 Segmental Gain in Retinoblastoma: Implications for Chemotherapy Response and Precision Oncology.

Elaine Huang, Shreya Sirivolu, Venkata Yellapantula, Prachi Kale, Peter Kuhn, James Hicks, Brianne Brown, Heidy Paniagua, Drishti Pandya, Rachana Shah and 2 more

Abstract read
In one paragraph

Article in JCO precision oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Elaine HuangThe Vision Center at Children's Hospital Los Angeles, Los Angeles, CA.ORCID 0000-0001-7434-7144
Shreya SirivoluThe Vision Center at Children's Hospital Los Angeles, Los Angeles, CA.ORCID 0009-0007-5871-9084
Venkata YellapantulaThe Vision Center at Children's Hospital Los Angeles, Los Angeles, CA.ORCID 0000-0003-1592-7741
Prachi KaleThe Vision Center at Children's Hospital Los Angeles, Los Angeles, CA.
Peter KuhnNorris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA.ORCID 0000-0003-2629-4505
James HicksNorris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA.ORCID 0000-0001-5353-4338
Brianne BrownThe Vision Center at Children's Hospital Los Angeles, Los Angeles, CA.ORCID 0000-0002-0852-1981
Heidy PaniaguaThe Vision Center at Children's Hospital Los Angeles, Los Angeles, CA.ORCID 0009-0007-0910-8332
Drishti PandyaThe Vision Center at Children's Hospital Los Angeles, Los Angeles, CA.
Rachana ShahDivision of Hematology-Oncology, Department of Pediatrics, Cancer and Blood Disease Institute, Children's Hospital Los Angeles, University of Southern California, Keck School of Medicine, Los Angeles, CA.
Jesse L BerryThe Vision Center at Children's Hospital Los Angeles, Los Angeles, CA.ORCID 0000-0002-8907-9100
Liya XuThe Vision Center at Children's Hospital Los Angeles, Los Angeles, CA.ORCID 0000-0002-5501-2039

Funding

Validation of an aqueous humor liquid biopsy for molecular prognostication and monitoring of children with retinoblastoma.R01CA282759 · NCI · CHILDREN'S HOSPITAL OF LOS ANGELES · PI Jesse L Berry · 2023 to 2026
$2.2M
Development of a surrogate liquid biopsy from the aqueous humor in retinoblastoma eyes.K08CA232344 · NCI · CHILDREN'S HOSPITAL OF LOS ANGELES · PI BERRY, JESSE L · 2018 to 2022
$1.1M
NCI NIH HHS K08 CA232344NCI NIH HHS R01 CA282759
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40834326
PMCPMC12379781

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.