ArticleArquivos brasileiros de cardiologia2025
Temporal Trends in the Epidemiology of Acute Rheumatic Fever: A Nationwide Analysis from 2008 to 2022.
Article in Arquivos brasileiros de cardiologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global prevalence and sex differences in rheumatic heart disease: a systematic review and updated meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Acute rheumatic fever and rheumatic heart disease in Latin America: a contemporary review of epidemiology.Lancet regional health. Americas · 2026Review
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9 authors.
Funding
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Abstract
backgroundAcute rheumatic fever (ARF) remains a significant public health challenge, especially in low- and middle-income countries. It disproportionately affects non-white populations in underprivileged regions and may lead to rheumatic heart disease (RHD), which has high morbidity and mortality.
objectivesAnalyze hospitalizations and deaths related to ARF in Brazil between 2008 and 2022, highlighting regional and demographic inequalities.
methodsWe conducted a cross-sectional study analyzing hospitalization and mortality data caused by ARF from 2008 to 2022 in Brazil, collected through the Hospital Information System (SIH/SUS). Data were stratified by demographics, region, and hospital visit type (urgent or elective) and analyzed using generalized linear autoregressive moving average models to assess the impact of age, sex, and race. Statistical significance was set at p < 0.05.
resultsOf 11,061 hospitalizations and 65 deaths from ARF, 53% were male and 16% were white. The 10-14-year-old age group had the highest hospitalization rates, while the 15-19-year-old group had more deaths. Hospitalizations were higher among non-white individuals and concentrated in Brazil's Northeast. Over time, ARF-related hospitalizations declined across all demographics, with a gradual convergence between male and female rates by 2022.
conclusionOur findings highlight a decline in ARF-related hospitalizations across regions and demographics, though disparities remain. There is no significant difference in ARF cases between men and women. The study highlights a correlation between socioeconomic factors and disease burden, with low-income groups experiencing a higher rate of ARF hospitalizations.
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