SynthesisRevista do Instituto de Medicina Tropical de Sao Paulo2025
Factors related to loss to follow-up among people living with HIV: a systematic review.
Synthesis in Revista do Instituto de Medicina Tropical de Sao Paulo, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Psychosocial vulnerabilities and loss to follow-up in people living with HIV in France.HIV medicine · 2026Article
- Strategies to improve retention in care among people living with HIV at health facilities in Manaus, Brazil: insight from health care providers.AIDS research and therapy · 2026Article
- Population mobility and disease progression in people living with HIV: a machine learning analysis of a 10-year dynamic cohort.Frontiers in public health · 2026Article
- Factors associated with loss to follow-up among people living with HIV at public health facilities in Manaus, Brazil: a multicentric study.BMC public health · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Loss to follow-up (LTFU) among people living with HIV (PLHIV) is a concerning reality in various healthcare services and can occur at any stage of HIV care. LTFU can lead to a decline in overall health and quality of life for PLHIV; moreover, antiretroviral therapy (ART) interruption increase the risk of HIV sexual transmission. This systematic review investigated factors related to LTFU among PLHIV. The review included sources from PubMed, Cochrane Library, Embase, and others. We included observational studies published in English, Spanish, or Portuguese, from January 1, 2004, to December 31, 2024. We identified 36 studies from 20 countries in North and South America, Europe, Asia, and Africa. The studies included 69,789 PLHIV, of whom 22% were classified as LTFU. The time frame used to define LTFU varied across studies, ranging from 14 to 365 days. The most frequently reported factors associated with LTFU were younger age, low educational level, financial instability, illicit drug use, stigma, absence of family and social support, and ART side effects. Other relevant factors included long commuting time to healthcare facilities, long waiting time at health units, and issues with provider-patient relationships. Multiple factors may contribute to LTFU among PLHIV in complex and context-dependent ways. To address this issue, healthcare services must develop a comprehensive understanding of the communities they assist, recognizing distinct subgroups and their specific needs. Public health policies should be implemented to promote continuous care for PLHIV, including early diagnosis, multidisciplinary assessment, and social support.
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