Evidence map›Paper›PMID 40834047›Full record

ArticleThe British journal of surgery2025

Decreasing aortic diameter and decreasing prevalence of infrarenal aortic aneurysms in a population-based screening programme.

Antti Siika, Anton Axelsson, Nina Fattahi, Joy Roy, Daniel Öhman, Anneli Linné, Rebecka Hultgren

Abstract read
In one paragraph

Article in The British journal of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Antti SiikaDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-2551-2526
Anton AxelssonDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Nina FattahiDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.ORCID 0009-0002-9504-8180
Joy RoyDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-5645-1260
Daniel ÖhmanDepartment of Cancer Prevention and Screening, Regional Cancer Centre Stockholm-Gotland, Stockholm, Sweden.
Anneli LinnéDepartment of Clinical Science and Education, Karolinska Institutet at Södersjukhuset, Stockholm, Sweden.
Rebecka HultgrenDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-8869-0493

Funding

Avtal om Läkarutbildning och ForskningKarolinska InstitutetStockholm County CouncilSwedish Heart-Lung Foundation 20210305Swedish Heart-Lung Foundation 20220282Swedish Heart-Lung Foundation 20230697
6 · The paper itself

Abstract

backgroundTemporal trends of infrarenal aortic diameters and their association with long-term mortality were explored in a population-based abdominal aortic aneurysm (AAA) screening programme. Additionally, changes in risk factor distribution and outcomes among the individuals with an AAA were analysed over the 14-year study period.

methodsIn this population-based cohort study between 2010 and 2023, all 65-year-old men who had been invited to screening for AAA were studied (152 000). Aortic diameter and date of death were extracted from the regional screening database.

resultsSome 117 120 men were examined, with reductions in mean(s.d.) aortic diameter (18.6(3.3) mm to 18.1(2.8) mm) and AAA prevalence (1.32% to 0.69%). The prevalence of small aortas (<17 mm) was 18.5% and that of subaneurysmal aortas (25-29 mm) was 1.1%. Initial aortic diameter showed a non-linear association with mortality (P < 0.001). The 5-year mortality was 3.8% for men with a normal aorta, 5.5% for men with a small aorta, 8.1% for men with a subaneurysmal aorta, and 9.5% for men with an AAA. The incidence of non-smoking men with an AAA remained constant, while a decline in the number of men with a smoking history was observed. Smoking cessation influenced timing of surgery and survival, with a 5-year mortality of 11.1% in current smokers versus 5.6% in non-smokers.

conclusionThere has been a decline in the prevalence of AAA and subaneurysmal aortas, and a slight rise in men with small aortas. Men with small or aneurysmatic aortas are at 1.5-2.5 times higher risk of mortality at 5 years compared with men with normal diameters. Smoking cessation halts the progression to AAA surgery and is associated with reduced mortality.

Indexed as

Aorta, AbdominalAortic Aneurysm, AbdominalMass ScreeningAgedHumansMalePrevalenceRisk Factors

Identifiers

PMID40834047
PMCPMC12366718

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.