ArticleJournal of the American Chemical Society2025
Enantioselective Synthesis of α-Oxygenated Ketones via Organocatalytic Formal O-H Bond Insertion of Sulfonium Ylides.
Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Organocatalytic enantioconvergent α-substitution of sulfonium salts by nitrogen nucleophiles.Chemical science · 2026Article
- Catalytic Enantioselective Multicomponent Reactions of Sulfoxonium Ylides Enabled by a Formal Rearrangement-A Versatile Entry to Enantioenriched α-Sulfanyl Carbonyl Compounds.Angewandte Chemie (International ed. in English) · 2026Article
- Harnessing PNature communications · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Described here is an example of organocatalytic enantioselective formal O-H bond insertion of α-carbonyl sulfur ylides, providing efficient access to highly enantioenriched ketones bearing a tertiary α-oxygenated stereocenter. This metal-free approach is complementary to the well-established metal-based diazo carbonyl chemistry, which has gained broad success for esters but not for ketones. The proper choice of a chiral thiourea catalyst in combination with
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Registered trials
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