Evidence map›Paper›PMID 40833689›Full record

ArticleEJNMMI physics2025

A fully automated AI-based method for tumour detection and quantification on [

Elin Trägårdh, Johannes Ulén, Olof Enqvist, Måns Larsson, Kristian Valind, David Minarik, Lars Edenbrandt

Abstract read
In one paragraph

Article in EJNMMI physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elin TrägårdhDepartment of Translational Medicine, Wallenberg Centre for Molecular Medicine, Lund University, Malmö, Sweden. Elin.tragardh@med.lu.se.ORCID http://orcid.org/0000-0002-7116-303X
Johannes UlénEigenvision AB, Malmö, Sweden.
Olof EnqvistEigenvision AB, Malmö, Sweden.
Måns LarssonEigenvision AB, Malmö, Sweden.
Kristian ValindDepartment of Translational Medicine, Wallenberg Centre for Molecular Medicine, Lund University, Malmö, Sweden.
David MinarikDepartment of Translational Medicine, Wallenberg Centre for Molecular Medicine, Lund University, Malmö, Sweden.
Lars EdenbrandtDepartment of Clinical Physiology, Sahlgrenska University Hospital, Gothenburg, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn this study, we further developed an artificial intelligence (AI)-based method for the detection and quantification of tumours in the prostate, lymph nodes and bone in prostate-specific membrane antigen (PSMA)-targeting positron emission tomography with computed tomography (PET-CT) images.

methodsA total of 1064 [

resultsThe sensitivities of the AI method were 85% for prostate tumour/recurrence, 91% for lymph node metastases and 61% for bone metastases (82%, 86% and 70% for manual readings and 66%, 88% and 71% for the old AI method). The PPVs of the AI method were 85%, 83% and 58%, respectively (63%, 86% and 39% for manual readings, and 69%, 70% and 39% for the old AI method). The correlations between manual and AI-based calculations of TLV and TLU ranged from r = 0.62 to r = 0.96.

conclusionThe performance of the newly developed and fully automated AI-based method for detecting and quantifying prostate tumour and suspected lymph node and bone metastases increased significantly, especially the PPV. The AI method is freely available to other researchers ( www.recomia.org ).

Indexed as

Artificial intelligenceCNNPET–CTProstate cancerPSMA

Identifiers

PMID40833689
PMCPMC12367631

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.