SynthesisMusculoskeletal surgery2026
Efficacy of pericapsular nerve group block (PENG) compared to local infiltration analgesia (LIA) after total hip arthroplasty: a systematic review and meta-analysis of randomized controlled trials.
Synthesis in Musculoskeletal surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- [Comparative observation of analgesic efficacy between liposomal bupivacaine and "cocktail" therapy following artificial intelligence-assisted direct anterior approach total hip arthroplasty: A prospective randomized controlled study].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026Trial
- [Peripheral regional anesthesia and analgesia: "the magnificent seven" for training].Die Anaesthesiologie · 2026Review
- Pericapsular nerve group block combined with lateral femoral cutaneous nerve block for hip surgery: a meta-analysis.Frontiers in pain research (Lausanne, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePain management after total hip arthroplasty (THA) is crucial for patient recovery and satisfaction. Various analgesic techniques exist, including the pericapsular nerve group (PENG) block and local infiltration analgesia (LIA). This study aims to compare the efficacy of PENG and LIA in postoperative pain management following THA.
methodsA random-effects meta-analysis of randomized controlled trials (RCTs) comparing PENG and LIA in primary THA was conducted. A systematic search of MEDLINE, Embase, Cochrane Library, and SCOPUS was performed up to October 24, 2024. Pain scores, opioid consumption, and secondary outcomes such as complications and postoperative nausea and vomiting (PONV) were analysed.
resultsFour RCTs were included, with 128 patients receiving PENG and 130 receiving LIA. Demographics, including age, BMI, ASA status, and surgery duration, were comparable. Pain scores at 6, 12, 24, and 48 h were higher in the PENG group but not statistically significant. At 24 h, cumulative opioid consumption was higher in the LIA group [4.23 mg (95% CI: 0.50-7.96) vs. 3.97 mg (95% CI: 0.24-7.70)] though not statistically significant (p = 0.92). At 48 h, PENG had higher cumulative opioid consumption [6.78 mg (95% CI: 1.04-12.52) vs. 6.18 mg (95% CI: 0.91-11.45)] though not statistically significant (p = 0.88). Secondary outcomes, including overall complication rates and PONV, showed no significant differences.
conclusionsPENG and LIA are comparable in terms of their effectiveness post THA. LIA is non-inferior to PENG in terms of postoperative pain scores, cumulative opioid consumption, overall complication rates and rates of PONV.
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