Observational studyJapanese journal of ophthalmology2026
Clinical characteristics of visual function, retinal ganglion cells, and nerve fiber layer in patients with adult craniopharyngioma.
Observational study in Japanese journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
purposeTo investigate the relationship between visual function, optical coherence tomography (OCT) parameters, and optic nerve bending before and after tumor resection in adult patients with craniopharyngioma. STUDY
designRetrospective observational study.
methodsWe retrospectively evaluated 22 eyes of 11 adult patients with craniopharyngioma who underwent tumor resection surgery. We assessed the preoperative and 1-month postoperative best-corrected visual acuity (BCVA), simple visual field impairment score (SVFIS) for visual field evaluation, 6-segmented macular ganglion cell layer (GCL) + inner plexiform layer (IPL) and 4-segmented circumpapillary retinal nerve fiber layer (cpRNFL) thickness, and optic nerve-canal bending angle (ONCBA).
resultsBilateral hemianopia was observed in 10 patients (91%), whilst homonymous hemianopia was observed in 1 patient (9%). The BCVA and SVFIS scores improved significantly postoperatively (both P <.001), and eyes with optic nerve bending had significantly worse preoperative BCVA and SVFIS (both P <.001), and the ONCBA was significantly correlated with preoperative BCVA, SVFIS, and GCL+IPL thickness in all areas. OCT detected superior nasal GCL+IPL thinning in 10 eyes (45%) and superior cpRNFL thinning in 2 eyes (9%).
conclusionIn adult patients with craniopharyngioma, GCL+IPL and cpRNFL thicknesses were associated with postoperative visual function recovery. The ONCBA was associated with preoperative visual dysfunction. ONCBA, GCL+IPL, and RNFL thicknesses may be useful for monitoring visual function in adult craniopharyngiomas preoperatively and postoperatively.
Indexed as
Identifiers
40833545What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.