Evidence map›Paper›PMID 40833456›Full record

ArticleOphthalmology and therapy2025

Secondary Trifocal Intraocular Lens Implantation in Dense Cataracts: A Promising Alternative to One-Step Surgery.

Jingyu Qu, Wei Xiao, Yue Wang, Ya Jiao, Shiqi Dong, Rong Xu

Abstract read
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Article in Ophthalmology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jingyu QuEye Institute of Shandong First Medical University, Qingdao Eye Hospital of Shandong First Medical University, Qingdao, 266000, People's Republic of China.
Wei XiaoDepartment of Ophthalmology, Wuhan Aier Hankou Eye Hospital, Wuhan, 430024, People's Republic of China.
Yue WangDepartment of Ophthalmology, Wuhan Aier Hankou Eye Hospital, Wuhan, 430024, People's Republic of China.
Ya JiaoDepartment of Ophthalmology, Wuhan Aier Hankou Eye Hospital, Wuhan, 430024, People's Republic of China.
Shiqi DongDepartment of Ophthalmology, Wuhan Aier Hankou Eye Hospital, Wuhan, 430024, People's Republic of China.
Rong XuDepartment of Ophthalmology, Wuhan Fourth Hospital, Gutian Third Road, Wuhan, 430030, Hubei, People's Republic of China. xurong_228@163.com.

Funding

National Natural Science Foundation of China 82401216Qingdao Eye Hospital Foundation for Incoming Doctoral Students W202210210004Qingdao Natural Science Foundation Youth Projec 23-2-1-145-zyyd-jchYouth Project of Natural Science Foundation of Shandong Province ZR2023QH340
6 · The paper itself

Abstract

introductionTo compare the benefits of secondary trifocal intraocular lens (IOL) implantations versus one-step IOL implantations in managing dense cataracts.

methodsPatients with dense cataracts, a preoperative axis length (AL) of 21.00-27.00 mm, and corneal astigmatism ≤ 1.00 D were enrolled at Wuhan Aier Hankou Eye Hospital. Patients unsuitable for femtosecond laser-assisted cataract surgeries (FLACS) were excluded. Patients who underwent one-step monofocal IOL implantations were involved in group A, and those who accepted two-step trifocal IOL implantations entered group B. Pre- and postoperative AL, corneal keratometry (K) value, visual acuity, and endothelial cell density (ECD) were measured. Postoperative spherical equivalent (SE), numerical error (NE), and mean absolute error (MAE) were calculated.

resultsApplying the inclusion/exclusion criteria, 42 eyes were finally included in group A, and 32 eyes were involved in group B. In group B, six eyes (15.79%) were identified as unsuitable for multifocal IOL (MIOL) implantation because of fundus diseases. Patients in group B achieved a greater proportion of SE and NE closer to 0 D. The postoperative MAE of group B was also obviously lower than that of group A. Uncorrected distant visual acuity (UDVA) of patients in group B was superior to that in group A during the 90-day postoperative follow-up period. Postoperative AL, surgically induced astigmatism (SIA), and ECD loss did not show significant differences between the two groups.

conclusionsCompared to one-step IOL implantation, the two-step approach allowed more accurate IOL power calculation, reduced refractive error, and better UDVA; did not increase SIA or ECD loss; and allowed for fundus disease screening, making it a good choice in dense cataracts for MIOL implantations.

trial registrationThis trial was registered with the Chinese Clinical Trial Registry ( http://www.chictr.org.cn/ ). TRIAL REGISTRATION NUMBER: ChiCTR2100043570.

Indexed as

AccuracyDense cataractRefractive errorSafetyTrifocal intraocular lens implantation

Identifiers

PMID40833456
PMCPMC12413368

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