Evidence map›Paper›PMID 40833310›Full record

ArticleJACC. Case reports2025

Wild-Type Transthyretin Amyloidosis in the Kidneys.

Tracy Joshi, Tatiana Prokaeva, Deepa M Gopal, Ashish Verma, Vaishali Sanchorawala, Hui Chen, Eric Burks, Surendra Dasari, Ellen D McPhail, Andrew Staron

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tracy JoshiAmyloidosis Center, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.
Tatiana ProkaevaAmyloidosis Center, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA; Department of Pathology & Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.
Deepa M GopalAmyloidosis Center, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.
Ashish VermaAmyloidosis Center, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.
Vaishali SanchorawalaAmyloidosis Center, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.
Hui ChenDepartment of Pathology & Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.
Eric BurksDepartment of Pathology & Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.
Surendra DasariDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.
Ellen D McPhailDepartment of Laboratory of Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Andrew StaronAmyloidosis Center, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA. Electronic address: Andrew.Staron@bmc.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wild-type transthyretin (ATTRwt) amyloidosis typically presents with restrictive cardiomyopathy. Kidney involvement is exceedingly rare. We report to our knowledge the first antemortem diagnosis of ATTRwt amyloidosis with kidney vasculature deposition in a patient presenting with progressive kidney failure. Notably, technetium-99m pyrophosphate scintigraphy showed no myocardial uptake. This case expands the known spectrum of organ involvement in ATTRwt amyloidosis and underscores the need to consider extracardiac manifestations in its diagnosis.

Indexed as

diagnosisextracardiac involvementkidney failurekidney involvementwild-type transthyretin amyloidosis

Identifiers

PMID40833310
PMCPMC12539439

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.