Evidence map›Paper›PMID 40833309›Full record

ArticleJACC. Case reports2025

Step Forward in Rheumatic Valve Disease: Simultaneous PTMC and TAVI as a Viable Treatment Strategy.

Varun Bhatia, Edwin Francis, Rajiv Chandrashekharan, Annu Jose

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Varun BhatiaDepartment of Cardiac Sciences, Aster Medcity, Kochi, India. Electronic address: 04.varun@gmail.com.
Edwin FrancisDepartment of Cardiac Sciences, Aster Medcity, Kochi, India.
Rajiv ChandrashekharanDepartment of Cardiac Sciences, Aster Medcity, Kochi, India.
Annu JoseDepartment of Cardiac Sciences, Aster Medcity, Kochi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRheumatic heart disease remains prevalent in low-income countries, often leading to combined severe mitral stenosis (MS) and aortic stenosis (AS). Although percutaneous transmitral commissurotomy (PTMC) is the standard treatment for severe MS with suitable anatomy, rheumatic AS is typically excluded from major transcatheter aortic valve implantation (TAVI) trials because of its noncalcific nature. CASE SUMMARY: We present a 72-year-old woman with severe rheumatic AS and MS who underwent simultaneous PTMC and TAVI. PTMC was performed via the right femoral vein using a 25-mm Accura balloon, followed by TAVI with a self-expanding Evolut-R valve, optimizing hemodynamics for her small aortic annulus. TAKE-HOME MESSAGES: Simultaneous PTMC and TAVI can be a safe and effective alternative to surgery in selected patients, offering a less invasive option for managing combined rheumatic valve disease. This case demonstrates its feasibility; however, further studies are needed to assess long-term outcomes.

Indexed as

mitral and aortic stenosisrheumatic valvular diseaseTAVI and PTMC

Identifiers

PMID40833309
PMCPMC12789748

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.